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Title: Comparability of functional MRI response in young and old during inhibition
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Keywords: Psychology
Issue Date: 2004
Publisher: Lippincott, Williams and Wilkins
Citation: Nielson, K., A., Langenecker, S. A., Ross, T. J., Garavan, H., Rao, S. M., Stein, E. A. ‘Comparability of functional MRI response in young and old during inhibition’ in NeuroReport, 15, 1, (2004), pp 129 - 133
Series/Report no.: NeuroReport
Abstract: AB When using fMRI to study age-related cognitive changes, it is important to establish the integrity of the hemodynamic response because, potentially, it can be affected by age and disease. However, there have been few attempts to document such integrity and no attempts using higher cognitive rather than perceptual or motor tasks. We used fMRI with 28 healthy young and older adults on an inhibitory control task. Although older and young adults differed in task performance and activation patterns, they had comparable hemodynamic responses. We conclude that activation during cognitive inhibition, which was predominantly increased in elders, was not due to vascular confounds or specific changes in hemodynamic coupling.
Description: PUBLISHED
ISSN: 0959-4965
Appears in Collections:Psychology (Scholarly Publications)

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