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dc.contributor.authorO'Mahony, Margaret
dc.date.accessioned2021-03-05T12:19:36Z
dc.date.available2021-03-05T12:19:36Z
dc.date.issued2021
dc.date.submitted2020en
dc.identifier.citationCarthy P, Ó Domhnaill A, O'Mahony M, Nolan A, Moriarty F, Broderick B, Hennessy M, Donnelly A, Naughton O, Lyons S. Local NO2 concentrations and asthma among over-50s in Ireland: A microdata analysis. International Journal of Epidemiology, 2021 Jan 23;49(6):1899-1908en
dc.identifier.otherY
dc.identifier.urihttp://hdl.handle.net/2262/95547
dc.descriptionPUBLISHEDen
dc.description.abstractBackground: Links between air pollution and asthma are less well established for older adults than some younger groups. Nitrogen dioxide (NO2) concentrations are widely used as an indicator of transport-related air pollution, and some literature suggests NO2 may directly affect asthma. Methods: This study used data on 8162 adults >50 years old in the Republic of Ireland to model associations between estimated annual outdoor concentration of NO2 and the probability of having asthma. Individual-level geo-coded survey data from The Irish Longitudinal Study on Ageing (TILDA) were linked to model-based estimates of annual average NO2 at 50 m resolution. Asthma was identified using two methods: self-reported diagnoses and respondents' use of medications related to obstructive airway diseases. Logistic regressions were used to model the relationships. Results: NO2 concentrations were positively associated with the probability of asthma [marginal effect (ME) per 1 ppb of airborne NO2 = 0.24 percentage points asthma self-report, 95% confidence interval (CI) 0.06-0.42, mean asthma prevalence 0.09; for use of relevant medications ME = 0.21 percentage points, 95% CI 0.049-0.37, mean prevalence 0.069]. Results were robust to varying model specification and time period. Respondents in the top fifth percentile of NO2 exposure had a larger effect size but also greater standard error (ME = 2.4 percentage points asthma self-report, 95% CI -0. 49 to 5.3). Conclusions: Associations between local air pollution and asthma among older adults were found at relatively low concentrations. To illustrate this, the marginal effect of an increase in annual average NO2 concentration from sample minimum to median (2.5 ppb) represented about 7-8% of the sample average prevalence of asthma.en
dc.format.extent1899en
dc.format.extent1908en
dc.language.isoenen
dc.relation.ispartofseriesInternational Journal of Epidemiology;
dc.relation.ispartofseries49;
dc.relation.ispartofseries6;
dc.rightsYen
dc.subjectAsthmaen
dc.subjectIrelanden
dc.subjectNitrogen dioxideen
dc.subjectOlder adultsen
dc.titleLocal NO2 concentrations and asthma among over-50s in Ireland: A microdata analysisen
dc.typeJournal Articleen
dc.contributor.sponsorEnvironmental Protection Agency (EPA)en
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/mmmahony
dc.identifier.rssinternalid224952
dc.identifier.doi10.1093/ije/dyaa074en
dc.rights.ecaccessrightsopenAccess
dc.relation.sourceTILDA dataseten
dc.subject.TCDThemeAgeingen
dc.subject.TCDThemeSmart & Sustainable Planeten
dc.subject.TCDTagAgeingen
dc.subject.TCDTagAgeing, Older People and Healthcareen
dc.subject.TCDTagAir Pollutionen
dc.subject.TCDTagEPIDEMIOLOGYen
dc.subject.TCDTagElderly Healthen
dc.subject.TCDTagEnvironmental Impacts of Transporten
dc.identifier.rssurihttps://doi.org/10.1093/ije/dyaa074
dc.subject.darat_thematicHealthen
dc.status.accessibleNen


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