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dc.contributor.authorEhrhardt, Carsten
dc.contributor.authorGobbo, Oliviero
dc.contributor.authorZurek, Magdalena
dc.contributor.authorTewes, Frederic
dc.contributor.authorCrémillieux, Yannick
dc.date.accessioned2019-11-06T10:58:09Z
dc.date.available2019-11-06T10:58:09Z
dc.date.issued2012
dc.date.submitted2012en
dc.identifier.citationGobbo, O.L., Zurek, M., Tewes, F., Erhardt, C. & Cémillieux, Y., Manganese: a new contrast agent for lung imaging?, Contrast Media Mol I, 7, 6, 2012, 542-546en
dc.identifier.otherY
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/full/10.1002/cmmi.1483
dc.identifier.urihttp://hdl.handle.net/2262/90156
dc.descriptionPUBLISHEDen
dc.description.abstractLung parenchyma remains one of the most difficult tissues to be imaged by means of magnetic resonance imaging (MRI). Several MRI techniques are routinely used for lung imaging. However, manganese-enhancement MRI (MEMRI) technique has not been associated with pulmonary MRI. Here, we evaluated T1-enhancement in the rat lung after a manganese instillation, using a 4.7 T magnet with a radial ultrashort echo time sequence. Our data showed that the signal intensity was increased in lungs receiving a manganese solution compared with a control solution to the lungs. MR signal enhancements above 30% were measured in lung parenchyma following 200 ml instillation of a 1 mM manganese chloride solution. MEMRI, therefore, may be a useful novel tool for enhancing signal intensity and image contrast in lung tissue.en
dc.format.extent542-546en
dc.language.isoenen
dc.relation.ispartofseriesContrast Media Mol I;
dc.relation.ispartofseries7;
dc.relation.ispartofseries6;
dc.rightsYen
dc.subjectMEMRIen
dc.subjectLung imagingen
dc.subjectManganeseen
dc.subjectAerosol contrast agenten
dc.subjectUTE lung MRIen
dc.titleManganese: a new contrast agent for lung imaging?en
dc.typeJournal Articleen
dc.contributor.sponsorScience Foundation Ireland (SFI)en
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/ogobbo
dc.identifier.peoplefinderurlhttp://people.tcd.ie/ehrhardc
dc.identifier.rssinternalid79792
dc.identifier.doihttp://dx.doi.org/10.1002/cmmi.1483
dc.rights.ecaccessrightsopenAccess
dc.subject.TCDThemeImmunology, Inflammation & Infectionen
dc.identifier.orcid_id0000-0003-4629-9485


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