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dc.contributor.advisorMitchell, Kevin
dc.contributor.authorDolan, Jackie N.
dc.date.accessioned2019-11-05T15:48:22Z
dc.date.available2019-11-05T15:48:22Z
dc.date.issued2013
dc.identifier.citationJackie N. Dolan, 'Functional analyses of a novel leucine-rich repeat-containing protein, Elfn1, in the mouse', [thesis], Trinity College (Dublin, Ireland). Department of Genetics, 2013, pp 235
dc.identifier.otherTHESIS 10236
dc.identifier.urihttp://hdl.handle.net/2262/90098
dc.description.abstractThe functional brain is critically dependent on a highly specific and perfectly timed gene-expression programme that underlies neuronal connectivity. Each step of this process, which includes cell migration, axon guidance, target selection and synaptogenesis, requires a vast number of molecules. While many genes with roles in these processes have been identified to date, the astonishing complexity and specificity of neural connections suggests that further molecules yetunidentified are involved. Leucine-rich repeat (LRR)-containing proteins are known to play crucial roles in the developing central nervous system. This led to the hypothesis that additional genes from this class of proteins could provide the necessary specificity of cellular interactions involved in neural connectivity.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). Department of Genetics
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15647136
dc.subjectGenetics & Microbiology, Ph.D.
dc.subjectPh.D. Trinity College Dublin.
dc.titleFunctional analyses of a novel leucine-rich repeat-containing protein, Elfn1, in the mouse
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 235
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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