Towards an improved understanding of local uterine innate immunity and histological change in postpartum cows : relevance to fertility?
Citation:
Aspinas Chapwanya, 'Towards an improved understanding of local uterine innate immunity and histological change in postpartum cows : relevance to fertility?', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2009, pp 216Download Item:
Chapwanya TCD THESIS 9305 Towards an.pdf (PDF) 86.17Mb
Abstract:
Uterine involution in postpartum (pp) cows is necessary for establishment of the next
pregnancy. Endometritis perturbs involution, impairs uterine function and causes
systemic illness leading to significant involuntary cow culling. This costs dairy farmers
and national exchequers €2.5 billion annually world-wide. At calving, bacteria enter the
uterus via the open cervix presumably stimulating a cascade of innate immune defence
events that culminate in transient uterine inflammation. In most cows this is followed by
the clearance of infection, resolution of inflammation and resumption of cyclic activity.
Author: Chapwanya, Aspinas
Advisor:
O'Farrelly, ClionaQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of Biochemistry and ImmunologyNote:
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