The effects of group II mGluR agonists on short-term depression and neutral coding in the rat dentate gyrus in vitro
Citation:John J. Kilbride, 'The effects of group II mGluR agonists on short-term depression and neutral coding in the rat dentate gyrus in vitro', [thesis], Trinity College (Dublin, Ireland). Department of Physiology, 2000, pp 196
Kilbride TCD THESIS 5493 The effects.pdf (PDF) 97.37Mb
Short-term depression is an activity-dependent reduction in synaptic efficacy which has been observed at a wide variety of synapses in the CNS, and is often attributed to a depletion of the available store of neurotransmitter. At the medial and lateral perforant path-granule cell synapses, short trains of stimuli at a range of frequencies between 0.5 Hz and 200 Hz resulted in a reversible depression of the evoked EPSP amplitude.
Author: Kilbride, John J.
Qualification name:Doctor of Philosophy (Ph.D.)
Publisher:Trinity College (Dublin, Ireland). Department of Physiology
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Type of material:thesis
Availability:Full text available