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dc.contributor.advisorO'Morain, Colm
dc.contributor.authorHyde, Denise K.
dc.date.accessioned2019-07-25T13:21:28Z
dc.date.available2019-07-25T13:21:28Z
dc.date.issued2000
dc.identifier.citationDenise K. Hyde, 'Helicobacter pylori infection : in vitro diagnostic methods, antimicrobial susceptibility testing, epidemiology of recrudescence and clarithromycin resistance', [thesis], Trinity College (Dublin, Ireland). Department of Microbiology, 2000, pp 286
dc.identifier.otherTHESIS 5899
dc.identifier.urihttp://hdl.handle.net/2262/88891
dc.description.abstractH. pylori is a Gram-negative, non-spore forming, curved bacterium that colonises the gastric epithelium of the human stomach. H. pylori is firmly established as an aetiological agent in peptic ulcer disease and successful eradication of this organism leads to duodenal ulcer cure. Culture of selected biopsy specimens that are known to be presumptively positive for H. pylori by a urease test might generate both accurate and cost-effective protocols for the diagnosis of this infection in clinical practice. Hence, the feasibility of culturing H. pylori from antral biopsy specimens of positive CLOtests was assessed. H. pylori was cultured from routine antral biopsy specimens in 34 of 38 (89%) H. pylori-infected patients and from antral biopsy specimens from positive CLOtests in 30 (79%) of these patients. Therefore, optimal isolation rates were achieved with routine biopsies. From a practical view point, it may be more reliable to store the routine microbiology biopsy at 4°C until the CLO test yields a positive result before sending the routine biopsy for culture.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). Department of Microbiology
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12464435
dc.subjectMicrobiology, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleHelicobacter pylori infection : in vitro diagnostic methods, antimicrobial susceptibility testing, epidemiology of recrudescence and clarithromycin resistance
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 286
dc.description.noteTARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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