Local modulation of pulmonary vascular function
Citation:Sean Patrick Gaine, 'Local modulation of pulmonary vascular function', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2000, pp 216
Gaine TCD THESIS 5621 Local modulation.pdf (PDF) 98.13Mb
The aim of the present study was to investigate the role of endothelial smooth muscle interaction in the local modulation of pulmonary vascular function. The main part of the work was carried out in isolated rings of porcine pulmonary artery suspended for isometric tension in an organ chamber preparation. In order to further investigate vascular responses, additional immunohistochemical, biochemical (enzyme assays, western blots) and molecular (Northern blots) methods were employed.
Author: Gaine, Sean Patrick
Advisor:Flavahan, Nicholas A.
Qualification name:Doctor of Philosophy (Ph.D.)
Publisher:Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics
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Type of material:thesis
Availability:Full text available