Browsing Pharmacy and Pharmaceutical Sciences by Title
Now showing items 405-424 of 594
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Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride
(2014)BACKGROUND: Silver nanoparticles (AgNPs) and fluoride (F) are pharmacological agents widely used in oral medicine and dental practice due to their anti-microbial/anti-cavity properties. However, risks associated with ... -
Pharmacological effects of a novel isosorbide-based butyrylcholinesterase inhibitor
(2008)Isosorbide-2-benzylcarbamate-5-benzoate, a novel butyrylcholinesterase inhibitor, shows interspecies variation in its inhibitory activity (IC50 of 4.3 nM for human plasma butyrylcholinesterase, but 1.09 ?M for mouse plasma ... -
Phase diagrams of polymer-dispersed liquid crystal systems of itraconazole - component immiscibility induced by molecular anisotropy
(2018)Liquid crystalline (LC) materials and their nonmedical applications have been known for decades, especially in the production of displays; however, the pharmaceutical implications of the LC state are inadequately appreciated, ... -
Physicochemical Characterization of a Co-Amorphous Atorvastatin-Irbesartan System with a Potential Application in Fixed-Dose Combination Therapy
(2021)The aim of this study was to characterize a 1:1 molar ratio of a pharmacologically relevant co-amorphous atorvastatin-irbesartan (ATR-IRB) system obtained by quench cooling of the crystalline ATR/IRB physical mixture for ... -
Physiochemical studies of diclofenac salts and the effect of basis excipients on their dissolution
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2001)This study involved investigation of the physicochemical properties of diclofenac salts prepared from a range of organic bases. The salts examined included five novel salts of diclofenac, prepared from the following bases: ... -
Phytochemical studies on Choisya x dewitteana 'Aztec Pearl'
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2018)The thesis is introduced with a review of the genus Choisya. Here emphasis is placed on the botany, traditional uses, phytochemistry and ethnopharmacological studies. The main classes of compounds found in the genus are ... -
Phytochemicals from food plant residues an approach to environmental clean-up.
(2011)Increased consumption of ‘ready to eat’ foods in modern lifestyle has resulted in several health problems. Natural health-protective and disease-preventive products are in great demand nowadays due to both consumers’ ... -
Platelet aggregation induced by Caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate
(2006)Formation of tumor cell-platelet aggregates facilitates hematogenous metastases. However, molecular mechanisms implicated in tumor cell-induced platelet aggregation (TCIPA) in colon cancer are unclear. To investigate ...