Browsing Pharmacy and Pharmaceutical Sciences by Title
Now showing items 300-319 of 559
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Mechanistics aspects of the release of drugs from hydrophilic polymer matrices
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2001)Hydrophilic polymers, which both swell and erode, are widely used to produce sustained release of drugs from monolithic matrices, and have been extensively reviewed in the literature (Alderman 1984), (Peppas and Korsmeyer ... -
Mechanochemical activation with cyclodextrins followed by compaction as an effective approach to improving dissolution of rutin
(2020)Rutin is one of the most important flavonoids with poor bioavailability. This work aimed at addressing the issue of poor biopharmaceutical performance of rutin by applying a combination of complexation with secondary ... -
Medication Safety in High-Risk Situations
(World Health Organisation, 2019)Each country participating in the third WHO Global Patient Safety Challenge: Medication Without Harm is urged to take early priority action to improve medication safety in high-risk situations and reduce harm by (5): ... -
Medication Safety in Polypharmacy
(World Health Organisation, 2019)Ensuring medication safety in polypharmacy is one of the key challenges for medication safety today. Due to the traditional focus of both medical research and health care delivery models on single-disease interventions, ... -
Medicine Maker: An Outreach Activity for Pharmaceutical Manufacturing and Health Literacy
(2022)Public engagement in medicine has become more important in promoting population health management and literacy. Medicine is a topic of great societal importance, and many public engagement activities have been developed ... -
Medicines use review pilot project
(Primary Care Group, Health Service Executive (HSE), 2012) -
Melanoma-associated antigen family protein-D4: clinical significance and functional relevance in breast cancer
(2010)Melanoma-associated antigen (MAGE) family genes are broadly expressed during development and are involved in the regulation of cell survival, cell cycle progression and apoptosis. MAGE family proteins are generally described ... -
Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis
(2010)Background: Malignant melanoma, generally described as incurable, is notoriously refractory to chemotherapy. The mechanisms contributing to this have not yet been defined and the contributions of drug efflux pumps, ... -
Mesenchymal Stem Cell Derived Extracellular Vesicles for Tissue Engineering and Regenerative Medicine Applications
(2020)Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in tissue engineering and regenerative medicine. However, recent evidence suggests that the beneficial effects of MSCs may be manifest ... -
Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies
(2015)Obesity is reaching epidemic proportions with recent worldwide figures estimated at 1.4 billion and rising year-on-year. Obesity affects all socioeconomic backgrounds and ethnicities and is a pre-requisite for metabolic ... -
Metformin Hydrochloride and Sitagliptin Phosphate Fixed-Dose Combination Product Prepared Using Melt Granulation Continuous Processing Technology
(2020)The development of oral solid dosage forms, such as tablets that contain a high dose of drug(s), requires polymers and other additives to be incorporated at low levels as possible, to keep the final tablet weight low, and, ... -
A method of separating extracellular vesicles from blood shows potential clinical translation, and reveals extracellular vesicle cargo gremlin-1 as a diagnostic biomarker
(2022)Extracellular vesicles (EVs) have potential as minimally invasive biomarkers. However, the methods most commonly used for EV retrieval rely on ultracentrifugation, are time-consuming, and unrealistic to translate to ... -
Methods in Apoptosis
(Elsevier Academic Press, 2006) -
MicroRNA Profiling of Exosomes
(Springer, 2017) -
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
(2019)The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of ...
