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dc.contributor.advisorScott, John
dc.contributor.authorO'Reilly, Sharleen Linette
dc.date.accessioned2019-05-01T14:45:55Z
dc.date.available2019-05-01T14:45:55Z
dc.date.issued2004
dc.identifier.citationSharleen Linette O'Reilly, 'The role of folate in the development of colorectal cancer', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2004, pp 354
dc.identifier.otherTHESIS 8050
dc.identifier.urihttp://hdl.handle.net/2262/86570
dc.description.abstractColorectal cancer is a leading cause of morbidity and mortality in Europe and the USA each year. Most large bowel cancers arise within pre-existing adenomatous polyps or adenomas. Several case-control and prospective studies have investigated the relationship between dietary folate intake and the risk of colorectal adenoma development, which is a well-established precursor of colorectal cancer. This project focused on establishing a method that would allow two techniques, colonic tissue folate calculation and the Comet assay, to be combined in a complementary fashion to investigate the relationship between purported DNA biomarkers, systemic and localised folate status and their role in the development of colorectal cancer.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12383089
dc.subjectClinical Medicine, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleThe role of folate in the development of colorectal cancer
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 354
dc.description.noteTARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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