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dc.contributor.advisorPrendergast., Patrick J.
dc.contributor.authorMcMahon, Louise Ann
dc.date.accessioned2019-05-01T13:26:38Z
dc.date.available2019-05-01T13:26:38Z
dc.date.issued2007
dc.identifier.citationLouise Ann McMahon, 'The effect of cyclic tensile loading and growth factors on the chondrogenic differentiation of bone-marrow derived mesenchymal stem cells in a collagen-glycosaminoglycan scaffold', [thesis], Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2007, pp 241
dc.identifier.otherTHESIS 8216
dc.identifier.urihttp://hdl.handle.net/2262/86500
dc.description.abstractAdult mesenchymal stem cells (MSCs) offer great potential in tissue engineering applications as they can be directed to differentiate along numerous lineages to produce a range of skeletal tissues, including the chondrogenic lineage. The importance of mechanical loading for the maintenance of skeletal tissues is well reported. The aim of this thesis was to demonstrate that the application of cyclic tensile strain to MSC-seeded collagen-GAG scaffolds regulates the chondrogenic differentiation process, in the presence of chondrogenic growth factors.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12962367
dc.subjectMechanical and Manufacturing Engineering, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleThe effect of cyclic tensile loading and growth factors on the chondrogenic differentiation of bone-marrow derived mesenchymal stem cells in a collagen-glycosaminoglycan scaffold
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 241
dc.description.noteTARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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