The role of beta-lactamase in low-level cephalosporin-resistant serratia marcescens
Citation:Celine M. Herra, 'The role of beta-lactamase in low-level cephalosporin-resistant serratia marcescens', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2002, pp 350
Herra TCD THESIS 6854 The role.pdf (PDF) 301.0Mb
In enterobacteria, high-level cephalosporin resistance is commonly mediated by constitutive over-production or derepression of chromosomal AmpC β-lactamase. This derepression is frequently associated with mutations in the ampD regulatory gene but altered AmpC expression may also result from mutation in the ampR regulatory gene or in the structural ampC gene.
Author: Herra, Celine M.
Qualification name:Doctor of Philosophy (Ph.D.)
Publisher:Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology
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Type of material:thesis
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