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dc.contributor.advisorKelleher, Dermot
dc.contributor.authorFitzmaurice, Karen Theresa
dc.date.accessioned2018-11-29T16:25:58Z
dc.date.available2018-11-29T16:25:58Z
dc.date.issued2011
dc.identifier.citationKaren Theresa Fitzmaurice, 'Defining the mechanism of protection of the class 1 Allele HLA-A *03 in a single source outbreak of Hepatitis C Virus', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2011, pp 278
dc.identifier.otherTHESIS 9616
dc.identifier.urihttp://hdl.handle.net/2262/85401
dc.description.abstractHepatitis C virus infects approximately 180 million persons worldwide and results in serious liver disease. Significant obstacles have hindered efforts to design an effective vaccine; in particular these include the profound heterogeneity that exists with respect to viral and host factors. The study of a unique cohort provides an unparalleled opportunity to define and unravel the correlates of a protective immune response in HCV. This cohort is comprised of a group of Irish women who inadvertently received batches of contaminated anti-D immunoglobulin in the late 1970s and is defined by common ethnicity, female gender, known time of infection as well as the presence of a common inoculum.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15124292
dc.subjectClinical Medicine, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleDefining the mechanism of protection of the class 1 Allele HLA-A *03 in a single source outbreak of Hepatitis C Virus
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 278
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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