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  • Genetic diagnosis and treatment of inherited retinopathies 

    Carrigan, Matthew (Trinity College (Dublin, Ireland). Department of Genetics, 2014)
    The first goal of this PhD was to improve and optimize a gene therapy based on the yeast protein Ndi 1 for Leber's Hereditary Optic Neuropathy (LHON), a mitochondrially-inherited retinal disorder. LHON is an incompletely ...