dc.contributor.advisor | Hun Mok, Kenneth | |
dc.contributor.author | Xie, Yongjing | |
dc.date.accessioned | 2017-06-28T12:37:18Z | |
dc.date.available | 2017-06-28T12:37:18Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Yongjing Xie, 'α-Lactalbumin-oleic acid complex : structure function dynamics', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015, pp 289 | |
dc.identifier.other | THESIS 10852 | |
dc.identifier.uri | http://hdl.handle.net/2262/80548 | |
dc.description.abstract | Human alpha-lactalbumin made lethal to tumor cells (HAMLET) and its analogues are partially unfolded protein-oleic acid complexes that exhibit selective tumoricidal activity normally absent in the native protein itself, in order to understand the nature of the interaction between a-lactalbumin and oleic acid moieties, charge-specific chemical modifications of lysine residues involving citraconylation, acetylation and guanidination were employed and the biophysical and biological properties of the wild type and chemically modified bovine a-lactalbumin-oleic acid complexes were characterized. | |
dc.format | 1 volume | |
dc.language.iso | en | |
dc.publisher | Trinity College (Dublin, Ireland). School of Biochemistry and Immunology | |
dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb16216079 | |
dc.subject | Biochemistry & Immunology, Ph.D. | |
dc.subject | Ph.D. Trinity College Dublin | |
dc.title | α-Lactalbumin-oleic acid complex : structure function dynamics | |
dc.type | thesis | |
dc.type.supercollection | thesis_dissertations | |
dc.type.supercollection | refereed_publications | |
dc.type.qualificationlevel | Doctoral | |
dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
dc.rights.ecaccessrights | openAccess | |
dc.format.extentpagination | pp 289 | |
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