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dc.contributor.advisorHun Mok, Kenneth
dc.contributor.authorXie, Yongjing
dc.date.accessioned2017-06-28T12:37:18Z
dc.date.available2017-06-28T12:37:18Z
dc.date.issued2015
dc.identifier.citationYongjing Xie, 'α-Lactalbumin-oleic acid complex : structure function dynamics', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015, pp 289
dc.identifier.otherTHESIS 10852
dc.identifier.urihttp://hdl.handle.net/2262/80548
dc.description.abstractHuman alpha-lactalbumin made lethal to tumor cells (HAMLET) and its analogues are partially unfolded protein-oleic acid complexes that exhibit selective tumoricidal activity normally absent in the native protein itself, in order to understand the nature of the interaction between a-lactalbumin and oleic acid moieties, charge-specific chemical modifications of lysine residues involving citraconylation, acetylation and guanidination were employed and the biophysical and biological properties of the wild type and chemically modified bovine a-lactalbumin-oleic acid complexes were characterized.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Biochemistry and Immunology
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb16216079
dc.subjectBiochemistry & Immunology, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleα-Lactalbumin-oleic acid complex : structure function dynamics
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 289
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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