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dc.contributor.advisorMurphy, Bruce
dc.contributor.authorSheridan, William
dc.date.accessioned2017-06-28T09:01:48Z
dc.date.available2017-06-28T09:01:48Z
dc.date.issued2014
dc.identifier.citationWilliam Sheridan, 'Manipulation of decellularized porcine scaffolds for tissue engineering vascular grafts', [thesis], Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2014, pp 260
dc.identifier.otherTHESIS 10476
dc.identifier.urihttp://hdl.handle.net/2262/80505
dc.description.abstractThe prevalence of vascular disease continues to increase worldwide, the treatment for which relies heavily on diseased vessel replacement. Tissue engineering vascular grafts potentially offers a new solution for addressing the shortage of autologous vessel grafts. Challenges such as suitable mechanical properties, viable cell sources, inefficient seeding techniques, lengthy manufacturing times, sustainable shelf life and high costs have hindered this translation. Decellularized scaffolds could potentially offer a solution to this clinical problem; however, their translation has been limited by their highly dense matrix architecture which can prevent cell repopulation.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15994710
dc.subjectMechanical and Manufacturing Engineering, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleManipulation of decellularized porcine scaffolds for tissue engineering vascular grafts
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 260
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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