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dc.contributor.advisorPidgeon, Graham
dc.contributor.authorCasey, Rory
dc.date.accessioned2017-01-18T10:50:34Z
dc.date.available2017-01-18T10:50:34Z
dc.date.issued2011
dc.identifier.citationRory Casey, 'Delineating the pro-carcinogenic pathways activated by obesity in Barrett's oesophagus', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery, 2011, pp 263
dc.identifier.otherTHESIS 9872
dc.identifier.urihttp://hdl.handle.net/2262/78840
dc.description.abstractIncidences of obesity in the developed world represent a worrying epidemic. Obesity is associated with increased rates of diabetes, cardiovascular disease and cancer. Oesophageal adenocarcinoma rates have increased in the last 25 years hand in hand with obesity, and clear correlations between the two have been demonstrated previously. A major risk factor for oesophageal adenocarcinoma is Barrett's oesophagus, a consequence of prolonged exposure to gastro oesophageal reflux disease (GORD). However, only a fraction of Barrett's patients with GORD will ultimately progress to oesophageal adenocarcinoma indicating that there must be other factors at play in the neoplastic progression of Barrett's oesophagus independent of GORD. The aim of this thesis was to identify pro-carcinogenic pathways activated by obesity in Barrett's oesophagus independent of GORD.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15319258
dc.subjectSurgery, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleDelineating the pro-carcinogenic pathways activated by obesity in Barrett's oesophagus
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 263
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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