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dc.contributor.advisorKelleher, Dermot
dc.contributor.authorPetrovic, Danijela
dc.date.accessioned2017-01-03T13:22:57Z
dc.date.available2017-01-03T13:22:57Z
dc.date.issued2009
dc.identifier.citationDanijela Petrovic, 'Mechanisms of immune evasion utilised by the Hepatitis C virus', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2009, pp 336
dc.identifier.otherTHESIS 8801
dc.identifier.urihttp://hdl.handle.net/2262/78590
dc.description.abstractHepatitis C virus (HCV) is a small, enveloped RNA virus which is distributed worldwide and according to the WHO the number of infected individuals is estimated to be approximately 170 million. HCV creates a heavy burden on a public health, since most HCV infections persist, leading in up to 80% of all cases to chronic hepatitis associated with liver fibrosis, cirrhosis and hepatocellular carcinoma. A successful immune response to HCV is characterised by a vigorous, sustained and multi-specific cellular response during the acute phase of infection. However, the persistence of HCV in infected individuals, is due mainly to its ability to evade immune defense, which it does using complex strategies to establish persistence and chronic disease.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb14170111
dc.subjectClinical Medicine, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleMechanisms of immune evasion utilised by the Hepatitis C virus
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 336
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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