Browsing Trinity College Dublin Theses & Dissertations by Subject "Obesity"
Now showing items 1-3 of 3
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Characterisation of circulating tumour cells in men with advanced prostate cancer and correlation with numbers of circulating and tissue-based inflammatory cells
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)Many men with prostate cancer present with advanced stage disease, and in these men treatment is directed towards improved survival and quality-of-life rather than cure. Exercise therapies are recognised to have benefits ... -
Exploring the influence of obesity, fatty acids, and current treatment modalities on the immune-metabolic profiles of adipose tissue in oesophageal cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Oesophageal adenocarcinoma (OAC) is a poor prognosis cancer with limited response rates to current standard of care treatments including chemotherapy and chemoradiotherapy. OAC has one of the strongest associations with ... -
Inflammasome Involvement in Barrett's and Oesophageal Adenocarcinoma
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)Barrett's oesophagus is an inflammatory condition and a neoplastic precursor to oesophageal adenocarcinoma (OAC). Inflammasome signalling pathways contribute to acute and chronic inflammation, and can be enhanced by obesity. ...