Browsing Trinity College Dublin Theses & Dissertations by Title
Now showing items 1563-1582 of 6303
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Diagnostic and prognostic biomarkers in ovarian cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2013)Ovarian cancer is the fifth most common cancer in women and the most frequent cause of gynaecological malignancy-related mortality in women. The vast majority present in advanced stages and this is due to lack of a reliable ... -
Dialogues with history : discourses of the Spanish Civil War and Francoist Dictatorsip in the Spanish novel (1996-2011)
(Trinity College (Dublin, Ireland). Department of Hispanic Studies, 2014)Drawing upon the novelistic and linguistic theories of Mikhail Bakhtin, this thesis investigates the narrative strategies used by four novels to inscribe, challenge or subvert current and past discourses about the Spanish ... -
Diaspora, gender and narrative journeys : Italian migrant women in Ireland
(Trinity College (Dublin, Ireland). Department of Sociology, 2008)Diaspora, Gender And Narrative Journeys: Italian Migrant Women In Ireland. This study concerns Italian migrant women in Ireland, who are the most invisible subjects of a forgotten yet ‘exceptional’ history of migration. ... -
Dicuil's De cursu solis lunaeque: Translation and commentary
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, 2023)Between 814 and 818, the Irish scholar Dicuil wrote five untitled books for the Carolingian Emperor Louis the Pious (778-840). This thesis provides the first textual analysis of this work in its entirety and a full ... -
Dielectric focusing elements for integrated optics
(Trinity College Dublin. School of Physics. Discipline of Physics, 2018)The ability to propagate light around a `circuit' on a single chip has an abundance of applications. Connecting different elements can bring huge functionality to a minuscule device---as evidenced by integrated electronic ... -
Dielectric Networks from solution processed 2D nanomaterials
(Trinity College Dublin. School of Physics. Discipline of Physics, 2022)Shortly after the demonstration of the existence of free-standing graphene, the need for large scale production of two-dimensional nanomaterials was met by the emergence of a solution processing method called liquid phase ... -
Diet and dietary patterns during pregnancy in nulliparous women in Ireland: a longitudinal cohort study
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2020)Background: The impact of maternal diet in pregnancy, for both the mother and baby, has been widely documented. Much of the research on diet in pregnancy has focused on the relationship between single nutrients and maternal ... -
Diet and other risk indicators associated with dental problems in Irish preschool children
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2018)This research used a data science approach to explore multilevel interactions among key aspects of child and primary caregiver (PCG) psychosocial and physical health, as well as diet and lifestyle factors affecting dental ... -
Dietary and genetic factors affecting the cholesteryl ester transfer protein and lipoprotein metabolism
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2001)The cholesteryl ester transfer protein (CETP) plays an inherent role in the redistribution of neutral lipids between high density lipoproteins (HDL) and very low density lipoproteins (VLDL) and low density lipoproteins ... -
Dietary conservatism in passerines : the influence of novel odour and novel colour
(Trinity College (Dublin, Ireland). Department of Zoology, 2001)This research was concerned with the way that passerine bird species use odour cues in isolation and in combination with colour cues to make decisions about new foods. Galliformes are known to demonstrate a disproportionately ... -
Dietary Conservatism: The Influences and Determinants of Alternative Foraging Strategies
(Trinity College Dublin. School of Natural Sciences. Discipline of Zoology, 2023)Dietary conservatism – the existence of alternative foraging strategies in response to novel foods – continues to be a little-known and understudied topic of animal behaviour. In every vertebrate population tested so far, ... -
Dietary fatty acids and diabetes mellitus : effect on postprandial lipoproteins and apolipoproteins
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2002)This thesis explores the relative merits of dietary polyunsaturated and monounsaturated fat in reducing the postprandial dyslipidaemia which is associated with diabetes. Of particular interest are the apolipoproteins which ... -
The Dietary Intake of Patients with Chronic Pancreatitis
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Chronic pancreatitis is a chronic inflammatory disorder that results in destruction of the endocrine and exocrine function of the pancreas. Due to loss of function, most patient suffer from malabsorption and malnutrition. ... -
Different patterns of gain and loss in genomic evolution
(Trinity College (Dublin, Ireland). Department of Genetics, 2008)Evolutionary forces may act on the genome at different levels, from the change of single nucleotides to the duplication or rearrangement of whole chromosomes. Some of these evolutionary processes can be responsible for ... -
Differential expression of differentation, key stemness and pathways genes and microRNAs and the role of Tgf-β in embryonal carinoma stem cells
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2010)Cancer stem cells (CSCs) identified in multiple malignancies has fuelled the belief that they drive primary tumourigenesis. Their persistence post-intervention contributes to metastasis, recurrence, self-renewal, thus ... -
Differential gene expression in diabetes : effects on postprandial lipoproteins
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2006)Diabetes is responsible for a large increase in cardiovascular risk which in many studies has not been reduced by improvement in blood sugar. The postprandial period in diabetes is associated with considerable disturbance ... -
Differential patterns of gene expression associated with metastasis in colon cancer
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2000)Metastatic spread is the main cause of colon cancer related death and therefore a greater understanding of this process is a prerequisite for improved treatment. The acquisition of metastatic properties confers tumour cells ... -
Differential patterns of gene expression associated with microsatellite instability and chromosomal instability in colorectal cancer
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2000)Two distinct pathways exist in sporadic colorectal cancer. The microsatellite instability pathway (MIN) is recognised by widespread instability caused by aberrant mismatch repair machinery. This genotype accounts for 15% ... -
Diffusion Weighted and Diffusion Tensor MRI-derived Apparent Diffusion Coefficient and Fractional Anisotropy Values as Biomarkers for Treatment Response in Breast Cancer
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)Background With increasing numbers of patients receiving neoadjuvant chemotherapy (NACT) for breast cancer and with multiple emerging drug agents, a reliable indicator of treatment response early in the course of ... -
Diffusion within fluorite structured materials and the effect of defects
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2018)There is a current global movement toward renewable sources and away from non- renewable energy sources. This can be attributed to the limited resources and harmful effects, both economic and environmental, of non-renewables. ...