Genome architecture and global transcriptional control in bacteria: making progress towards a unified model?
Item Type:Journal Article
Citation:Dorman CJ, Genome architecture and global transcriptional control in bacteria: making progress towards a unified model?, Nature Reviews Microbiology, 11, 5, 2013, 349 - 355
Charles J.pdf (PDF) 3.171Mb
Data obtained with advanced imaging techniques, chromosome conformation capture methods, bioinformatics and molecular genetics, together with insights from polymer physics and mechanobiology, are helping to refine our understanding of the spatiotemporal organization of the bacterial nucleoid and its gene expression programmes. Here, I discuss the proposal that, in addition to DNA topology and nucleoid-associated proteins, gene regulation is an important organizing principle of nucleoid architecture.
Science Foundation Ireland (SFI)
Published online 3 April 2013
Author: DORMAN, CHARLES
Type of material:Journal Article
Series/Report no:Nature Reviews Microbiology
Availability:Full text available