Show simple item record

dc.contributor.authorO'DOHERTY, JOHNen
dc.date.accessioned2014-12-11T10:41:53Z
dc.date.available2014-12-11T10:41:53Z
dc.date.issued2013en
dc.date.submitted2013en
dc.identifier.citationMcNamee,Daniel D., Rangel,Antonio A., O'Doherty,John P. J.P., Category-dependent and category-independent goal-value codes in human ventromedial prefrontal cortex, Nature Neuroscience, 16, 4, 2013, 479-485en
dc.identifier.issn10976256en
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/72415
dc.descriptionPUBLISHEDen
dc.description.abstractTo choose between manifestly distinct options, it is suggested that the brain assigns values to goals using a common currency. Although previous studies have reported activity in ventromedial prefrontal cortex (vmPFC) correlating with the value of different goal stimuli, it remains unclear whether such goal-value representations are independent of the associated stimulus categorization, as required by a common currency. Using multivoxel pattern analyses on functional magnetic resonance imaging (fMRI) data, we found a region of medial prefrontal cortex to contain a distributed goal-value code that is independent of stimulus category. More ventrally in the vmPFC, we found spatially distinct areas of the medial orbitofrontal cortex to contain unique category-dependent distributed value codes for food and consumer items. These results implicate the medial prefrontal cortex in the implementation of a common currency and suggest a ventral versus dorsal topographical organization of value signals in the vmPFCen
dc.description.sponsorshipWe thank V. Chib and E. Boorman for helpful discussions, and J. Stanley for assistance. This work was funded by Science Foundation Ireland grant 08/IN.1/B1844 and a grant from the Gordon and Betty foundation (to J.P.O.)en
dc.format.extent479-485en
dc.language.isoenen
dc.relation.ispartofseriesNature Neuroscienceen
dc.relation.ispartofseries16en
dc.relation.ispartofseries4en
dc.rightsYen
dc.subjectvmPFCen
dc.subject.lcshvmPFCen
dc.titleCategory-dependent and category-independent goal-value codes in human ventromedial prefrontal cortexen
dc.typeJournal Articleen
dc.contributor.sponsorScience Foundation Ireland (SFI)en
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/odoherjpen
dc.identifier.rssinternalid98324en
dc.identifier.doihttp://dx.doi.org/10.1038/nn.3337en
dc.rights.ecaccessrightsopenAccess
dc.contributor.sponsorGrantNumber08/IN.1/B1844en


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record