Browsing Clinical Medicine by Author "BAIRD, ANNE-MARIE"
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Epigenetic Regulation of Glucose Transporters in Non-Small Cell Lung Cancer
O'BYRNE, KEN; BAIRD, ANNE-MARIE; GRAY, STEVEN (MDPI, 2011)Due to their inherently hypoxic environment, cancer cells often resort to glycolysis, or the anaerobic breakdown of glucose to form ATP to provide for their energy needs, known as the Warburg effect. At the same time, ... -
Epigenetics Underpinning the Regulation of the CXC (ELR+) Chemokines in Non-Small Cell Lung Cancer
O'BYRNE, KEN; BAIRD, ANNE-MARIE; GRAY, STEVEN (PLoS, 2011)Background: Angiogenesis may play a role in the pathogenesis of Non-Small Cell Lung cancer (NSCLC). The CXC (ELR+) chemokine family are powerful promoters of the angiogenic response. Methods: The expression of the CXC ... -
IL-23R is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer.
DOHERTY, DEREK; BAIRD, ANNE-MARIE; GRAY, STEVEN; O'BYRNE, KEN (2013)The Interleukin-23 (IL-23)/IL-23R signaling axis is an important inflammatory pathway, involved in the stimulation and regulation of the T helper (Th) 17 lymphocytes, resulting in the production of IL-17. Aside from ...