Browsing Dental Science by Date of Publication
Now showing items 1-20 of 219
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Candida dubliniensis: An update
(1999)The increased incidence of fungal infections during the last decade has been well-documented. Given that one of the most important factors contributing to this phenomenon is the increased numbers of immunocompromised ... -
An investigation into the molecular epidemiology of Candida dubliniensis
(Trinity College (Dublin, Ireland). School of Dental Science, 2002)Candida dubliniensis is a recently described Candida species primarily associated with oral candidosis in Human Immunodeficiency Virus (HlV)-infected and AIDS patients. The population structure of C. dubliniensis was ... -
Investigation into the molecular mechanisms of itraconazole resistance in Candida dubliniensis
(Trinity College (Dublin, Ireland). School of Dental Science, 2003)Candida dubliniensis is a recently identified yeast species primarily associated with oral carriage and infection in HIV-infected individuals. Previous studies have shown that only a small number of clinical isolates are ... -
COMPARATIVE GENOMICS USING CANDIDA ALBICANS DNA MICROARRAYS REVEALS ABSENCE AND DIVERGENCE OF VIRULENCE ASSOCIATED GENES IN CANDIDA DUBLINIENSIS
(2004)Candida dubliniensis is a pathogenic yeast species closely related to Candida albicans. However, it is less frequently associated with human disease and displays reduced virulence in animal models of infection. We have ... -
Reduced azole susceptibility in genotype 3 C. dubliniensis isolates associated with increased CdCDR1 and CdCDR2 expression.
(2005)Candida dubliniensis is a recently identified yeast species primarily associated with oral carriage and infection in HIV-infected individuals. The species can be divided into at least four genotypes on the basis of the ... -
NOVEL 5-FLUCYTOSINE-RESISTANT CLADE OF CANDIDA DUBLINIENSIS FROM SAUDI ARABIA AND EGYPT IDENTIFIED BY CD25 FINGERPRINTING.
(2005)DNA fingerprinting of Candida dubliniensis isolates using the species-specific probe Cd25 previously showed that this species consists of two distinct groups, termed Cd25 group I and Cd25 group II. The present study ... -
An investigation into the biofilm-associated bacterial contamination of dental chair units and dental unit output water supplies and its control
(Trinity College (Dublin, Ireland). School of Dental Science, 2005)Many modern medical devices, including dental chair units (DCUs), are potential reservoirs of infection as they can harbour biofilm-associated microorganisms. This study investigated several aspects of DCUs related to ... -
AZOLE SUSCEPTIBILITY AND RESISTANCE IN CANDIDA DUBLINIENSIS
(2005)Candida dubliniensis is a recently described species of pathogenic yeast that shares many phenotypic features with Candida albicans. It is primarily associated with oral colonization and infection in HIV-infected individuals. ... -
DIFFERENTIAL REGULATION OF THE TRANSCRIPTIONAL REPRESSOR NRG1 ACCOUNTS FOR ALTERED HOST CELL INTERACTIONS IN CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS
(2007)Candida dubliniensis is genetically closely related to C. albicans, but causes fewer infections in humans and exhibits reduced virulence and filamentation in animal models of infection. We investigated the role of the ... -
Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans
(Elsevier, 2007)Candida albicans and Candida dubliniensis are very closely related yeast species. In this study, we have conducted a thorough comparison of the ability of the two species to produce hyphae and their virulence in two ... -
DIFFERENTIAL REGULATION OF THE TRANSCRIPTIONAL REPRESSOR NRG1 ACCOUNTS FOR ALTERED HOST CELL INTERACTIONS IN CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS
(Blackwell Publishing, 2007-09)Candida dubliniensis is genetically closely related to C. albicans, but causes fewer infections in humans and exhibits reduced virulence and filamentation in animal models of infection. We investigated the role of the C. ... -
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
(2008)Abstract: Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually(1). To identify genetic factors that modify disease risk, we conducted a genome- wide association study by ... -
MULTILOCUS SEQUENCE TYPING REVEALS THAT THE POPULATION STRUCTURE OF Candida dubliniensis IS SIGNIFICANTLY LESS DIVERGENT THAN THAT OF Candida albicans
(2008)he pathogenic yeast Candida dubliniensis is phylogenetically very closely related to Candida albicans, and both species share many phenotypic and genetic characteristics. DNA fingerprinting using the species-specific probe ... -
Multilocus sequence typing reveals that the population structure of Candida dubliniensis is significantly less divergent than that of Candida albicans.
(2008)The pathogenic yeast Candida dubliniensis is phylogenetically very closely related to Candida albicans, and both species share many phenotypic and genetic characteristics. DNA fingerprinting using the species-specific probe ... -
Head and neck squamous cell carcinoma in the young: a spectrum or a distinct group? Part 1.
(2009)While most head and neck squamous carcinoma (HNSCC) occurs in older people, an increasing number of young patients are being affected worldwide, with up to 5.5% <40. These are predominantly oral and oropharyngeal cancers. ... -
Head and neck squamous cell carcinoma in the young: a spectrum or a distinct group? Part 2.
(2009)A recent increase in the number of young patients (often nonsmokers) developing head and neck squamous cell carcinoma (HNSCC) has been documented, however, there remains no clear evidence to support the significance of any ... -
Investigating the effect of skeletal pattern in determining articulator settings for prosthodontic rehabilitation: an in-vivo study
(Trinity College (Dublin, Ireland). School of Dental Science, 2009)During extensive prosthodontic treatment the use of an accurately adjusted articulator is recommended to simulate some mandibular movements. An in-vivo clinical study was undertaken to assess any possible effect of underlying ... -
Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress
(Wiley-Blackwell, 2009)Candida albicans is more pathogenic than Candida dubliniensis. However, this disparity in virulence is surprising given the high level of sequence conservation and the wide range of phenotypic traits shared by these two ... -
AVIAN-ASSOCIATED AND HUMAN ISOLATES OF Candida dubliniensis ARE GENETICALLY DISTINCT
(2009)When Candida dubliniensis isolates obtained from seabird excrement and from humans in Ireland were compared by using multilocs sequence typing, 13 of 14 avian isolates were genetically distinct from human isolates. The ...