Browsing Microbiology by Subject "SPI-2"
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Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium
(2021)DNA gyrase is an essential type II topoisomerase that is composed of two subunits, GyrA and GyrB and has an A 2 B 2 structure. Although both subunits are required in equal proportions to form DNA gyrase, the gyrA and gyrB ... -
FNR is a regulator of Salmonella pathogenicity Island 2 in Salmonella Typhimurium
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Microbiology, 2019)During infection, S. Typhimurium employs Salmonella pathogenicity island (SPI)-encoded type three secretion systems (T3SS) 1 and 2 to invade and survive in host cells. However, expression of SPI-2 is seen at the epithelial ...