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dc.contributor.authorFAGAN, ANDREW JOHNen
dc.date.accessioned2013-05-03T09:02:42Z
dc.date.available2013-05-03T09:02:42Z
dc.date.issued2012en
dc.date.submitted2012en
dc.identifier.citationA.J. Stone, B. Lennon, J.E. Browne, J.F.M. Meaney, A.J. Fagan, Effect of motion on the quantification accuracy of whole-body DWIBS, Magnetic Resonance Materials in Physics, Biology and Medicine, 25, 2012, 263 - 266en
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/66438
dc.descriptionPUBLISHEDen
dc.description.abstractBackground & Methods: Diffusion-weighted whole-body imaging with background body signal subtraction (DWIBS) was introduced as a qualitative approach to detecting metastases in the body. A liver-mimicking phantom with embedded tumours, which could be moved to replicate respiratory motion, was developed to assess its ability to accurately quantify ADC values. Results: Mean tumour ADC values were unaltered by the motion; however a significant (p<0.05) increase in the spread of ADC values was measured, even for relatively large tumours. Conclusions: These findings may be of significance in cancer therapy monitoring where subtle changes in ADC histograms may reveal changes in tumour heterogeneity.en
dc.description.sponsorshipHealth Research Board (Ireland)en
dc.format.extent263en
dc.format.extent266en
dc.language.isoenen
dc.relation.ispartofseriesMagnetic Resonance Materials in Physics, Biology and Medicineen
dc.relation.ispartofseries25en
dc.rightsYen
dc.subjectDWIBSen
dc.subjectQuantificationen
dc.subjectADCen
dc.subjectMotionen
dc.titleEffect of motion on the quantification accuracy of whole-body DWIBSen
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/fagananen
dc.identifier.rssinternalid80251en


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