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dc.contributor.authorO'MARA, SHANEen
dc.contributor.authorPASSECKER, JOHANNESen
dc.contributor.authorCHAH, EHSANen
dc.contributor.authorDELLA CHIESA, ANDREAen
dc.contributor.authorHOK, VINCENTen
dc.date.accessioned2011-11-07T14:19:16Z
dc.date.available2011-11-07T14:19:16Z
dc.date.issued2011en
dc.date.submitted2011en
dc.identifier.citationPassecker J, Hok V, Della-Chiesa A, Chah E, O'Mara SM, Dissociation of dorsal hippocampal regional activation under the influence of stress in freely behaving rats., Frontiers in Behavioral Neuroscience, 5, 2011, 66-en
dc.identifier.issn1662-5153en
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/60551
dc.descriptionPUBLISHEDen
dc.description.abstractStress has deleterious effects on brain, body, and behavior in humans and animals alike. The present work investigated how 30-min acute photic stress exposure impacts on spatial information processing in the main sub-regions of the dorsal hippocampal formation [CA1, CA3, and dentate gyrus (DG)], a brain structure prominently implicated in memory and spatial representation. Recordings were performed from spatially tuned hippocampal and DG cells in rats while animals foraged in a square arena for food. The stress procedure induced a decrease in firing frequencies in CA1 and CA3 place cells while sparing locational characteristics. In contrast to the CA1-CA3 network, acute stress failed to induce major changes in the DG neuronal population. These data demonstrate a clear dissociation of the effects of stress on the main hippocampal sub-regions. Our findings further support the notion of decreased hippocampal excitability arising from behavioral stress in areas CA1 and CA3, but not in DG.en
dc.format.extent66en
dc.language.isoenen
dc.relation.ispartofseriesFrontiers in Behavioral Neuroscienceen
dc.relation.ispartofseries5en
dc.rightsYen
dc.subjectNeuroscienceen
dc.subjectStressen
dc.titleDissociation of dorsal hippocampal regional activation under the influence of stress in freely behaving rats.en
dc.typeJournal Articleen
dc.contributor.sponsorScience Foundation Ireland (SFI)en
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/smomaraen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/hokven
dc.identifier.peoplefinderurlhttp://people.tcd.ie/dellachaen
dc.identifier.rssinternalid75725en
dc.identifier.doihttp://dx.doi.org/10.3389/fnbeh.2011.00066en
dc.contributor.sponsorGrantNumber8AA G22112en
dc.subject.TCDThemeNeuroscienceen
dc.identifier.rssurihttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194099/?tool=pubmeden
dc.identifier.orcid_id0000-0001-8087-8531en


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