Tunable bromomagnesium thiolate Tishchenko reaction catalysts: efficient intermolecular aldehyde-trifluoromethylketone coupling
Citation:
L. Cronin, F.Manoni, C. J. O' Connor and S.J. Connon*, Tunable bromomagnesium thiolate Tishchenko reaction catalysts: efficient intermolecular aldehyde-trifluoromethylketone coupling, Angewandte Chemie International Edition, 49, 17, 2010, 3045-3048Download Item:

Abstract:
A new thiolate-catalyzed Tishchenko reaction inspired by biochemical processes features exceptionally good control over the catalyst's steric/electronic properties. The isolation of reaction intermediates provided valuable insights into the reaction mechanism, which in turn has allowed the development of the first cross-Tishchenko coupling reactions between aldehydes and activated ketones
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Grant Number
Science Foundation Ireland (SFI)
Author's Homepage:
http://people.tcd.ie/connonsDescription:
PUBLISHEDHighlighted in Synfacts (2010, 817).
Author: CONNON, STEPHEN
Type of material:
Journal ArticleCollections:
Series/Report no:
Angewandte Chemie International Edition49
17
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Full text availableKeywords:
Biochemistry, disproportionation, Grignard reagents, homogeneous catalysis, synthetic methods, Tishchenko reactionSubject (TCD):
Nanoscience & MaterialsLicences: