Browsing Medical Gerontology by Title
Now showing items 317-336 of 372
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Safety and tolerability of Tilt Testing and Carotid Sinus Massage in the octogenarians
(2016)Objective: to evaluate the safety and tolerability of Tilt Testing (TT) and Carotid Sinus Massage (CSM) in octogenarians with unexplained syncope. Methods: patients consecutively referred for transient loss of consciousness ... -
SART and individual trial mistake thresholds: predictive model for mobility decline
(2021)The Sustained Attention to Response Task (SART) has been used to measure neurocognitive functions in older adults. However, simplified average features of this complex dataset may result in loss of primary information and ... -
A scoping review of the changing landscape of Geriatric Medicine in undergraduate medical education: curricula, topics and teaching methods
(2021)Purpose: The world’s population is ageing. Therefore, every doctor should receive geriatric medicine training during their undergraduate education. This review aims to summarise recent developments in geriatric medicine ... -
Self-report versus electronic medical record recorded healthcare utilisation in older community-dwelling adults: Comparison of two prospective cohort studies.
(2018)Self-reported measures of healthcare utilisation are often used in longitudinal cohort studies involving older community-dwelling people. The aim of this study is to compare healthcare utilisation rates using patient ... -
Self-reported cardiovascular conditions are associated with falls and syncope in community-dwelling older adults.
(2015)Background: with increasing age, causes of syncope are more often of cardiac origin. Syncope in older persons is often mistaken for falls. Data regarding the association between specific cardiovascular conditions, falls ... -
Severity and Mortality of SARS-COV-2 infection and 25-hydroxyvitamin D concentration: a metanalysis
(2021)Introduction: There is increasing scientific interest in the possible association between hypovitaminosis D and the risk of SARS-CoV-2 infection severity and/or mortality. Objective: To conduct a metanalysis of the ... -
Severity of SARS-Cov-2 infection and angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers: a meta-analysis
(2020)Background: The mechanism of entry of SARS-CoV-2 into the human host cell is through the ACE2 receptor. During the pandemic, a hypothesis has been proposed that angiotensin-converting enzyme inhibitors (ACEIs) and ... -
The SHARE operationalized frailty phenotype: a comparison of two approaches.
(2013)PURPOSE: the phenotype defined by Fried et al. is one of the main operationalizations of frailty. Santos-Eggimann et al. pioneered the adaptation of the phenotype criteria to the Survey of Health, Ageing and Retirement ... -
Should prevention of falls start earlier? Coordinated analyses of harmonised data on falls in middle-aged adults across four population-based cohort studies
(2018)The prevalence of risk factors for falls increases during middle-age, but the prevalence of falls in this age-range is often overlooked and understudied. The aim was to calculate the prevalence of falls in middle-aged ... -
Sleep habits in older adults in Ireland: Associations with physical and cognitive function
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2021)Sleep acts as the rest cycle for the body, during which restorative processes such as muscle growth, repair and memory consolidation occur. Sleep duration and chronotype have been identified as areas of interest to improve ... -
SNP variation in the promoter of the PRKAG3 gene and association with meat quality traits in pig.
(2012)Background The PRKAG3 gene encodes the ?3 subunit of adenosine monophosphate activated protein kinase (AMPK), a protein that plays a key role in energy metabolism in skeletal muscle. Non-synonymous single nucleotide ... -
Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation
(2017)Low socioeconomic status (SES) is associated with earlier onset of age-related chronic conditions and reduced life-expectancy, but the underlying biomolecular mechanisms remain unclear. Evidence of DNA-methylation differences ... -
Social disadvantage and social isolation are associated with a higher resting heart rate: evidence from The Irish Longitudinal Study on Ageing (TILDA)
(2015)OBJECTIVES: A high resting heart rate (RHR) represents a major risk factor for cardiovascular disease and individuals from poorer backgrounds have a higher RHR compared with their more advantaged peers. This study ... -
Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.
(2019)Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious exposures across the ... -
Socioeconomic status, non-communicable disease risk factors, and walking speed in older adults: multi-cohort population based study.
(British Medical Association, 2018)Objective: To assess the association of low socioeconomic status and risk factors for non-communicable diseases (diabetes, high alcohol intake, high blood pressure, obesity, physical inactivity, smoking) with loss of ... -
Statin use in adults at high risk of cardiovascular disease mortality: Cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA)
(2015)Objectives This study aims to examine the extent to which statins are used by adults at high risk of cardiovascular disease (CVD) compared to European clinical guidelines. The high-risk groups examined are those with (1) ...