Browsing Medical Gerontology by Title
Now showing items 49-68 of 372
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Biomarker Signatures of Two Phenotypical Pre-Frailty Types in The Irish Longitudinal Study on Ageing
(2022)Abstract: We investigated the biomarker signatures of two previously reported phenotypical prefrailty (PF) types in the first wave of The Irish Longitudinal Study on Ageing (TILDA): PF1 (unexplained weight loss and/or ... -
Biomarkers of delirium risk in older adults: a systematic review and meta-analysis
(2023)Delirium is a neuropsychiatric syndrome associated with increased morbidity and mortality in older patients. The aim of this study was to review predictive biomarkers of delirium in older patients to gain insights into ... -
Blood Pressure Signal Entropy as a Novel Marker of Physical Frailty: Results from the FRAILMatics Clinical Cohort
(2022)In this study we investigated the association between information entropy in short length blood pressure signals and physical frailty status, in a group of patients aged 50+ recruited from the Falls and Syncope Unit at ... -
Breastfeeding and risk of overweight and obesity at nine years of age
(2012)Whether breastfeeding is protective against the development of childhood overweight and obesity remains the subject of considerable debate. Although a number of meta-analyses and syntheses of the literature have concluded ... -
Building resilience and reversing frailty: a randomised controlled trial of a primary care intervention for older adults
(2023)Background: There is a need for effective primary care interventions that help older people combat frailty and build resilience. Objective: To study the effectiveness of an optimised exercise and dietary protein ... -
Cardiovascular associations of falls and syncope in the elderly
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2017)The principle aims of this doctoral investigation are to provide new insights into the relationship between cardiovascular disease (CVD) and falls in the elderly population in Ireland. The rapidly ageing global demographic ... -
Cardiovascular Autonomic Nervous System, Blood Pressure Instability and Brain Health in Older Adults: Population-Based Perspectives
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2019)The aim of this thesis is to provide new insights into the shared pathways by which the cardiovascular autonomic nervous system underpins optimal regulation of affect and cognitive function in older adults. Ageing is ... -
Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention.
(2018)Objective: to examine the associations of cardiovascular disease (CVD) and cardiovascular risk factors with frailty. Design: a cross-sectional study. Setting: the Irish Longitudinal Study on Ageing (TILDA). Participants: ... -
Cardiovascular signal entropy predicts all-cause mortality: evidence from The Irish Longitudinal Study on Ageing (TILDA)
(2022)In this study, the relationship between cardiovascular signal entropy and the risk of seven-year all-cause mortality was explored in a large sample of community-dwelling older adults from The Irish Longitudinal Study on ... -
Care home residents admitted to hospital through the emergency pathway: characteristics and associations with inpatient mortality
(2018)Background Routinely collected hospital information could help to understand the characteristics and outcomes of care home residents admitted to hospital as an emergency. Methods This retrospective 2-year ser vice evaluation ... -
Change in perceived stress and 2-year change in cognitive function among older adults: The Irish Longitudinal Study on Ageing
(Wiley, 2018)Prolonged or severe stress can adversely affect older adults' cognitive function, but population‐based studies investigating this relationship over time are rare. Previous studies have largely focused on stress either ... -
Change in skeletal muscle associated with unplanned hospital admissions in adult patients: a systematic review and meta-analysis
(2019)Objectives: The primary objective of the review was to describe change that occurs in skeletal muscle during periods of unplanned hospitalisation in adult patients. The secondary objective was to examine the relationship ... -
Changes in Muscle Strength and Physical Function in Older Patients During and After Hospitalisation: a Prospective Repeated-Measures Cohort Study
(2020)Aim: To investigate changes in knee-extension strength and physical function in older adults during and after acute hospital admission, and the contributions of illness severity, frailty and sedentary activity to changes ... -
Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid
(2023)Objective: Orthostatic intolerance (OI) is common in Long Covid. Physical counterpressure manoeuvres (PCM) may improve OI in other disorders. We characterised the blood pressure-rising effect of PCM using surface ... -
Characterising the Blood Pressure Response to Physical Counterpressure Manoeuvres Using Surface Electromyography in Adults with Long Covid
(2023)Objective: Orthostatic intolerance (OI) is common in Long Covid. Physical counterpressure manoeuvres (PCM) may improve OI in other disorders. We characterised the blood pressure-rising effect of PCM using surface ... -
Characteristics and outcomes of older persons attending the emergency department: a retrospective cohort study.
(2014)Background: The analysis of routinely collected hospital data informs the design of specialist services for at-risk older people. Aim: Describe the outcomes of a cohort of older emergency department (ED) attendees and ... -
Choice reaction time and subsequent mobility decline: Prospective observational findings from The Irish Longitudinal Study on Ageing (TILDA)
(2020)Background: Cognitive and motor function in ageing are intertwined, but whether slower motor response time (MRT) to a cognitive stimulus could herald accelerated mobility decline is unknown. Using data from The Irish ... -
Circulating micronutrient biomarkers are associated with three measures of frailty: Evidence from The Irish Longitudinal Study on Ageing (TILDA).
(2019)Objectives: To examine the associations between 3 frailty instruments and circulating micronutrients in a large representative sample of older adults. Design: Cross-sectional data from a nationally representative cohort ... -
Clinical clustering of eight orthostatic haemodynamic patterns in The Irish Longitudinal Study on Ageing (TILDA)
(2020)Background: Orthostatic hypotension (OH) can be assessed with non-invasive continuous beat-to-beat haemodynamic monitoring during active stand (AS) testing; this yields large volumes of data outside the scope ...