Browsing Medical Gerontology by Title
Now showing items 21-40 of 372
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Altered lives in a time of crisis: The impact of the COVID-19 pandemic on the lives of older adults in Ireland. Findings from The Irish Longitudinal Study on Ageing
(TILDA, 2021)The ongoing pandemic of SARS-CoV-2, a novel coronavirus that causes COVID-19 infection and disease, is threatening healthcare systems globally as well as in Ireland. (1) The COVID-19 pandemic, and public health-associated ... -
An alternative method for Frailty Index cut-off points to define frailty categories.
(2013)PURPOSE: the Frailty Index (FI) is a popular operationalization of frailty. FI cut-off points have been proposed to define, regardless of age, frailty categories with increasing risk. Here, an alternative method is ... -
Amnesia for loss of consciousness is common in vasovagal syncope.
(2011)The aim of this study was to determine the prevalence of amnesia for loss of consciousness (A-LOC) in those who have a history suggestive of vasovagal syncope (VVS) and who develop syncope on head-up tilt (HUT) table ... -
An investigation of the incidence of falling and risk factors for falls in adults with advanced cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2012)The principal aims of this doctoral investigation were to identify the incidence of falls and risk factors for falling in adults with advanced cancer. -
An investigation of the safety, efficacy, and possible mechanisms of action, of the antihypertensive nilvadipine, in patients with mild moderate Alzheimer's disease
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2011)This doctoral investigation endeavoured to explore how patients with Alzheimer's disease (AD) would respond to treatment with the antihypertensive nilvadipine. Initially I reviewed the complex relationship between blood ... -
Analysis and biophysical modelling of baroreflex stimulation with applications in syncope and falls : a neural engineering approach
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Medical Gerontology, 2011)Carotid Sinus Hypersensitivity (CSH) is an age related disorder, and a common cause of recurrent falls and syncope in the elderly. CSH is prevalent in patients with Dementia and Parkinson's disease and is a strong predictor ... -
Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study
(2020)Background: Some studies have suggested that the insertion(I)/deletion(D) polymorphism of the Angiotensin-Converting Enzyme (ACE) gene may be associated with human longevity, especially in centenarians. However, this ... -
Anticholinergic medications in patients admitted with cognitive impairment and falls (AMiCI). The impact of hospital admission on anticholinergic cognitive medication burden. Results of a multi centre observational study
(2018)What is known and objective: Drugs with anticholinergic properties increase the risk of falls, delirium, chronic cognitive impairment, and mortality and counteract procholinergic medications used in the treatment of dementia. ... -
Antidepressants are Independently Associated with Gait Deficits in Single and Dual Task Conditions
(2015)Objectives This study examined the relationships between late-onset depressive symptoms, antidepressants, and single and dual task gait in older adults. Design Cross-sectional study. Setting The Irish Longitudinal ... -
Antidepressants strongly influence the relationship between depression and heart rate variability: findings from The Irish Longitudinal Study on Ageing (TILDA)
(2015)Background: Heart rate variability (HRV) is known to be reduced in depression; however, is unclear whether this is a consequence of the disorder or due to antidepressant medication. Methods: We analysed data on 4750 ... -
Approximate entropies of resting state continuous neurocardiovascular physiological signals are associated with physical frailty in older adults
(2021)Frailty in older adults is characterised by dysregulation in multiple physiological systems. The frailty phenotype is defined on the basis of exhaustion, unexplained weight loss, weakness, slowness and low physical activity ... -
The Association between Blood Pressure, Cerebral Perfusion and Late Life Depression
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2020)Background: While late life is generally characterised by contentment and happiness, depression in later life confers an independently increased risk of early mortality, cognitive and functional decline and nursing home ... -
The association between clinical frailty and walking speed in older hospitalised medical patients: a retrospective observational study
(2017)This study aims to further evaluate the use of the clinical frailty scale (CFS) by assessing its correlation with usual walking speed (UWS) in older medical inpatients. Methods Retrospective observational study in an English ... -
The association between cognitive impairment and functional outcome in hospitalised older patients: a systematic review and meta-analysis
(2017)Background: in hospitalised older adults, cognitive impairments are common and may be associated with functional outcomes. Our aim was to systematically review this association.Method: we systematically searched MEDLINE, ... -
Association between low serum vitamin d and Increased mortality and severity due to COVID-19: reverse causality?
(2022)We are very close to completing two years since the start of the COVID-19 pandemic. Even though vaccines have been developed and applied to more than 4 billion people in the world, SARS-CoV-2 continues to be a challenge ... -
Association of cognition with functional trajectories in patients admitted to geriatric wards: a retrospective observational study
(2017)Aim: Impaired cognition is common among older patients admitted to acute hospitals, but its association with functional trajectories has not been well studied. Methods: A retrospective observational study was carried ... -
The association of geriatric syndromes with hospital outcomes
(2017)BACKGROUND: Frailty, history of dementia (HoD), and acute confusional states (ACS) are common in older patients admitted to hospital. OBJECTIVE: To study the association of frailty (≥6 points in the Clinical Frailty Scale ...