Show simple item record

dc.contributor.authorSULLIVAN, DEREKen
dc.contributor.authorMORAN, GARYen
dc.contributor.authorCOLEMAN, DAVIDen
dc.date.accessioned2010-06-22T16:08:28Z
dc.date.available2010-06-22T16:08:28Z
dc.date.issued2005en
dc.date.submitted2005en
dc.identifier.citationPINJON E, MORAN GP, COLEMAN DC, SULLIVAN DJ, AZOLE SUSCEPTIBILITY AND RESISTANCE IN CANDIDA DUBLINIENSIS, BIOCHEMICAL SOCIETY TRANSACTIONS, 33, 5, 2005, 1210 - 1214en
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/40199
dc.descriptionPUBLISHEDen
dc.description.abstractCandida dubliniensis is a recently described species of pathogenic yeast that shares many phenotypic features with Candida albicans. It is primarily associated with oral colonization and infection in HIV-infected individuals. Isolates of C. dubliniensis are generally susceptible to commonly used azole antifungal agents; however, resistance has been observed in clinical isolates and can be induced by in vitro exposure. Molecular mechanisms of azole resistance in C. dubliniensis include increased drug efflux, modifications of the target enzyme and alterations in the ergosterol biosynthetic pathway.en
dc.format.extent1210en
dc.format.extent1214en
dc.language.isoenen
dc.relation.ispartofseriesBIOCHEMICAL SOCIETY TRANSACTIONSen
dc.relation.ispartofseries33en
dc.relation.ispartofseries5en
dc.rightsYen
dc.subjectDental Scienceen
dc.subjectMicrobiologyen
dc.subjectCandida dubliniensisen
dc.titleAZOLE SUSCEPTIBILITY AND RESISTANCE IN CANDIDA DUBLINIENSISen
dc.typeJournal Articleen
dc.contributor.sponsorHealth Research Board (HRB)en
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/djsullvnen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/dcolemanen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/gmoranen
dc.identifier.rssinternalid29356en
dc.identifier.doihttp://dx.doi.org/10.1128/AAC.49.4.1312-1318.2005en
dc.subject.TCDThemeGenes & Societyen
dc.subject.TCDThemeImmunology, Inflammation & Infectionen
dc.identifier.rssurihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16246083&dopt=Abstracten
dc.identifier.orcid_id0000-0003-0195-9697en


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record