Key role for clumping factor B in Staphylococcus aureus nasal colonization of humans.
Citation:Wertheim, HF, Walsh, E, Choudhurry, R, Melles, DC, Boelens, HA, Miajlovic, H, Verbrugh, HA, Foster, T, van Belkum, A, Key role for clumping factor B in Staphylococcus aureus nasal colonization of humans., PLoS medicine, 5, 1, 2008, e17
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Staphylococcus aureus permanently colonizes the vestibulum nasi of one-fifth of the human population, which is a risk factor for autoinfection. The precise mechanisms whereby S. aureus colonizes the nose are still unknown. The staphylococcal cell-wall protein clumping factor B (ClfB) promotes adhesion to squamous epithelial cells in vitro and might be a physiologically relevant colonization factor.
Type of material:Journal Article
Series/Report no:PLoS medicine
Availability:Full text available