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dc.contributor.authorCOEN, ROBERTen
dc.contributor.authorLAWLOR, BRIANen
dc.date.accessioned2010-04-12T14:36:57Z
dc.date.available2010-04-12T14:36:57Z
dc.date.issued2009en
dc.date.submitted2009en
dc.identifier.citationBlanco-Campal A, Coen RF, Lawlor BA, Walsh JB, Burke TE, Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task., Journal of the International Neuropsychological Society : JINS, 15, 1, 2009, 154-159en
dc.identifier.issn1355-6177en
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/38893
dc.descriptionPUBLISHEDen
dc.description.abstractWe investigated the relative discriminatory efficacy of an event-based prospective memory (PM) task, in which specificity of the instructions and perceptual salience of the PM cue were manipulated, compared with two widely used retrospective memory (RM) tests (Rivermead Paragraph Recall Test and CERAD-Word List Test), when detecting mild cognitive impairment of suspected Alzheimer's disease etiology (MCI-AD) (N = 19) from normal controls (NC) (N = 21). Statistical analyses showed high discriminatory capacity of the PM task for detecting MCI-AD. The Non-Specific-Non-Salient condition proved particularly useful in detecting MCI-AD, possibly reflecting the difficulty of the task, requiring more strategic attentional resources to monitor for the PM cue. With a cutoff score of <4/10, the Non-Specific-Non-Salient condition achieved a sensitivity = 84%, and a specificity = 95%, superior to the most discriminative RM test used (CERAD-Total Learning: sensitivity = 83%; specificity = 76%). Results suggest that PM is an early sign of memory failure in MCI-AD and may be a more pronounced deficit than retrospective failure, probably reflecting the greater self-initiated retrieval demands involved in the PM task used. Limitations include the relatively small sample size, and the use of a convenience sample (i.e. memory clinic attenders and healthy active volunteers), reducing the generalizability of the results, which should be regarded as preliminary. (JINS, 2009, 15, 154-159.).en
dc.format.extent154-159en
dc.language.isoenen
dc.relation.ispartofseriesJournal of the International Neuropsychological Society : JINSen
dc.relation.ispartofseries15en
dc.relation.ispartofseries1en
dc.rightsYen
dc.subjectProspective memoryen
dc.subjectMild cognitive impairmenten
dc.subjectMemory disordersen
dc.subjectNeuropsychological testsen
dc.subjectDementiaen
dc.subjectEarly detectionen
dc.titleDetection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task.en
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/rcoenen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/lawlorbaen
dc.identifier.rssinternalid64145en
dc.identifier.doihttp://dx.doi.org/10.1017/S1355617708090127en
dc.subject.TCDThemeNeuroscienceen
dc.identifier.rssurihttp://dx.doi.org/10.1017/S1355617708090127en


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