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dc.contributor.authorPRENDERGAST, PATRICKen
dc.contributor.authorKELLY, DANIELen
dc.contributor.authorLALLY, CAITRIONAen
dc.date.accessioned2010-02-17T14:00:39Z
dc.date.available2010-02-17T14:00:39Z
dc.date.issued2009en
dc.date.submitted2009en
dc.identifier.citationMichael Early; Catriona Lally; Patrick J. Prendergast; Daniel J. Kelly, Stresses in peripheral arteries following stent placement: a finite element analysis, Computer Methods in Biomechanics and Biomedical Engineering, 12, 1, 2009, 25, 33en
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/38226
dc.descriptionPUBLISHEDen
dc.description.abstractThe success of stents to restore blood flow in atherosclerotic peripheral arteries is low relative to coronary arteries. It has been shown that joint flexion induces a mechanical environment that makes stent placement in these arteries highly incompatible, and damage and destruction of stents has been recorded. However, the effect of this environment on the stresses in the arteries is unknown. It is hypothesised that the stresses induced in arteries as a result of this mechanical environment could be sufficient to explain the relatively low success rates. To investigate this hypothesis, a finite element model of the stent-artery interaction was developed. Following stent expansion, bending was simulated by applying a displacement boundary condition to the artery. It is found that high stresses occur at the proximal/distal ends of the stent. As high stress and vascular injury are hypothesised to cause restenosis, the results presented here suggest that the mechanical environment of peripheral arteries could be the predominant cause of high restenosis rates.en
dc.format.extent25en
dc.format.extent33en
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.relation.ispartofseriesComputer Methods in Biomechanics and Biomedical Engineeringen
dc.relation.ispartofseries12en
dc.relation.ispartofseries1en
dc.rightsYen
dc.subjectperipheral stenten
dc.subjectfinite element analysisen
dc.subjectartery bendingen
dc.subjectrestenosisen
dc.titleStresses in peripheral arteries following stent placement: a finite element analysisen
dc.typeJournal Articleen
dc.contributor.sponsorEnterprise Irelanden
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/pprenderen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/kellyd9en
dc.identifier.peoplefinderurlhttp://people.tcd.ie/lallycaen
dc.identifier.rssinternalid63611en
dc.identifier.doihttp://dx.doi.org/10.1080/10255840802136135en
dc.subject.TCDThemeNext Generation Medical Devicesen
dc.identifier.rssurihttp://www.informaworld.com/smpp/content~db=all~content=a903092273~tab=linkingen


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