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dc.contributor.authorWALSH, PATRICKen
dc.date.accessioned2010-01-18T16:47:24Z
dc.date.available2010-01-18T16:47:24Z
dc.date.issued2004en
dc.date.submitted2004en
dc.identifier.citationWalsh, P.T., Taylor, D.K. and Turka, L.A., Tregs and transplantation tolerance, Journal of Clinical Investigation, 114, 10, 2004, 1398-1403en
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/35826
dc.descriptionPUBLISHEDen
dc.description.abstractThe induction and maintenance of immune tolerance to transplanted tissues constitute an active process involving multiple mechanisms that work cooperatively to prevent graft rejection. These mechanisms are similar to inherent tolerance toward self antigens and have a requirement for active immunoregulation, largely T cell mediated, that promotes specific unresponsiveness to donor alloantigens. This review outlines our current understanding of the Treg subsets that contribute to allotolerance and the mechanisms by which these cells exert their effects as well as their potential for therapy.en
dc.format.extent1398-1403en
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.relation.ispartofseriesJournal of Clinical Investigationen
dc.relation.ispartofseries114en
dc.relation.ispartofseries10en
dc.rightsYen
dc.subjectBiochemistry
dc.titleTregs and transplantation toleranceen
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/walshp10en
dc.identifier.rssinternalid62884en
dc.identifier.doihttp://dx.doi.org/10.1172/JCI23238en
dc.subject.TCDThemeImmunology, Inflammation & Infectionen
dc.identifier.rssurihttp://dx.doi.org/10.1172/JCI23238


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