The role of right fronto-parietal cortex in cognitive control: Common activations for ?cues-to-action? and response inhibition.
Item Type:Journal Article
Citation:Fassbender, C., Simoes-Franklin, C., Murphy, K., Hester, R., Meaney, J., Robertson, I. H., & Garavan, H. 'The role of right fronto-parietal cortex in cognitive control: Common activations for ?cues-to-action? and response inhibition' in Journal of Psychophysiology, 20, 4, (2006), pp 86 - 296
The role of a right fronto-parietal network in cognitive control.pdf (published (author copy) peer-reviewed) 633.1Kb
Seemingly distinct cognitive tasks often activate similar anatomical networks. For example, the right fronto-parietal cortex is active across a wide variety of paradigms suggesting that these regions may subserve a general cognitive function. We utilized fMRI and a GO/NOGO task consisting of two conditions, one with intermittent unpredictive "cues-to-attend" and the other without any "cues-to-attend," in order to investigate areas involved in inhibition of a prepotent response and top-down attentional control. Sixteen subjects (5 male, ages ranging from 20 to 30 years) responded to an alternating sequence of the letters X and Y and withheld responding when the alternating sequence was broken (e.g., when X followed an X). Cues were rare stimulus font-color changes, which were linked to a simple instruction to attend to the task at hand. We hypothesized that inhibitions and cues, despite requiring quite different responses from subjects, might engage similar top-down attentional control processes and would thus share a common network of anatomical substrates. Although inhibitions and cues activated a number of distinct brain regions, a similar network of right dorsolateral prefrontal and inferior parietal regions was active for both. These results suggest that this network, commonly activated for response inhibition, may subserve a more general cognitive control process involved in allocating top-down attentional resources.
Author: GARAVAN, HUGH PATRICK
Publisher:Hogrefe & Huber Publishers
Type of material:Journal Article
Series/Report no:Journal of Psychophysiology
Availability:Full text available