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dc.contributor.authorKELLY, DANIEL
dc.contributor.editorTomasz, Lekszycki & Pawel Maldyken
dc.date.accessioned2009-04-14T12:19:13Z
dc.date.available2009-04-14T12:19:13Z
dc.date.issued2005
dc.date.submitted2005en
dc.identifier.citationMechanobiological models of Skeletal Tissue Differentiation, Tomasz Lekszycki & Pawel Maldyk, Biomaterials in Orthopaedic Practice, Warsaw, Polish Academy of Sciences,, 2005, 1, 20, DJ Kellyen
dc.identifier.otherY
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/29046
dc.descriptionPUBLISHEDen
dc.description.abstractMechanical forces may act within tissues at the cellular level to regulate biological processes, a field of study that has been termed mechanobiology. The aim of computational mechanobiology is to derive sets of equations that describe the changes in cell expression, and hence the composition, structure and phenotype of tissues, as a function of the applied mechanical stimuli. This chapter will attempt to review the different mechanobiological models that have been developed to relate mechanical stimuli to tissue differentiation. The majority of these models have been used to simulate tissue differentiation during fracture healing or osteochondral defect repair. Based on this review, a number of recommendations will be made by the author for the future development of computational models of tissue differentiation.en
dc.format.extent1en
dc.format.extent20en
dc.format.extent2065117 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherPolish Academy of Sciencesen
dc.rightsYen
dc.subjectMechanobiologyen
dc.subjectTissue Differentiationen
dc.subjectFinite Element Modelen
dc.subjectFracture Healingen
dc.subjectOsteochondral defect repairen
dc.titleMechanobiological models of Skeletal Tissue Differentiationen
dc.typeBook Chapteren
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/kellyd9


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