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  • IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment 

    Campbell, Matthew; Augustine, Josy; Pavlou, Sofia; Ali, Imran; Harkin, Kevin; Ozaki, Ema; Stitt, Alan W.; Xu, Heping; Chen, Mei (2019)
    Background: Interleukin-33 (IL-33) belongs to the IL-1 cytokine family and resides in the nuclei of various cell types. In the neural retina, IL-33 is predominately expressed in Müller cells although its role in health ...
  • Sterile inflammation and age-related macular degeneration 

    Ozaki, Ema (Trinity College (Dublin, Ireland). Department of Genetics, 2015)
    Age-related macular degeneration (AMD) is the leading cause of legal blindness in elderly individuals in the developed world, estimated to affect 196 million people worldwide by 2020 (Wong et ai, 2014). AMD primarily affects ...