Browsing School of Genetics & Microbiology by Subject "AEBP2"
Now showing items 1-2 of 2
-
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
(2018)The polycomb repressive complex 2 (PRC2) consists of core subunits SUZ12, EED, RBBP4/7, and EZH1/2 and is responsible for mono-, di-, and tri-methylation of lysine 27 on histone H3. Whereas two distinct forms exist, PRC2.1 ... -
Understanding the role of accessory components in regulation of the Polycomb Repressive Complex 2 in mESCs and cancer
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2022)Polycomb Repressive Complex 2 is a chromatin regulatory complex composed of core subunits EZH1/2, EED, SUZ12 and RBBP4/7, around which several accessory components assemble in a mutually exclusive manner to form structurally ...