Browsing Administrative Staff Authors (Scholarly Publications) by Author "REILLY, MARY"
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A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors
WINDLE, HENRY; GILMER, JOHN FRANCIS; KELLEHER, DERMOT P; KEOGH, BRIAN; REILLY, MARY (2011)The design, synthesis and delivery potential of a new type of benzenesulfonamide cyclo-oxygenase-2 (COX-2) inhibitor prodrug is investigated using celecoxib. The approach involves a double prodrug that is activated first ...