Browsing Administrative Staff Authors (Scholarly Publications) by Sponsor "Irish Cancer Society"
Now showing items 1-4 of 4
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Cellular proliferation and activation of NF kappa B are induced by autocrine production of tumor necrosis factor alpha in the human T lymphoma line HuT 78
(The American Society for Biochemistry and Molecular Biology, 1995)Tumor necrosis factor (TNF) is a pleiotropic cytokine which has both cytotoxic and proliferative effects. HuT 78, a T-cell line derived from a Sezary lymphoma, is resistant to the cytotoxic effects of TNF, suggesting that ... -
Expression of CD44 and its variants on gastric epithelial cells of patients with Helicobacter pylori colonisation
(BMJ, 1996)BACKGROUND--Studies have suggested that expression of the adhesion molecule CD44 may be of prognostic importance in gastric cancer. In addition, there is strong evidence that Helicobacter pylori has a role in gastric cancer. ... -
Protein kinase C isoform expression in CD45RA+ and CD45RO+ T lymphocytes
(Blackwell, 1995)Differences in levels of specific enzymes utilized in intracellular signalling could be a factor in the distinct signalling properties observed in memory and naive T cells. We have studied the expression of both classical ... -
Regulation of CD3 expression in a protein kinase C isozyme-deficient T-cell line
(British Society for Immunology, 1993)Using the T-cell lymphoma line HuT 78, and a clone derived from HuT 78, designated K-4, the role of protein kinase C (PKC) isozymes in the expression of a variety of T-cell surface antigens was investigated. HuT 78 expresses ...