Browsing Administrative Staff Authors by Author "BOKDE, ARUN"
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Altered Brain Activation During a Verbal Working Memory Task in Subjects with Amnestic Mild Cognitive Impairment.
BOKDE, ARUN; HAMPEL, HARALD (2010)In subjects with Mild Cognitive Impairment (MCI) memory disorders indicate a high risk for conversion to Alzheimer?s disease (AD). The objective of this study was to delineate the differences in brain activation between ... -
Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis.
BOKDE, ARUN (2015)The genetic component of alcohol use disorder is substantial, but monozygotic twin discordance indicates a role for nonheritable differences that could be mediated by epigenetics. Despite growing evidence associating ... -
Brain atrophy in primary progressive aphasia involves the cholinergic basal forebrain and Ayala's nucleus
BOKDE, ARUN (2014)Primary progressive aphasia (PPA) is characterized by left hemispheric fronto-temporal cortical atrophy. Evidence from anatomical studies suggests that the nucleus subputaminalis (NSP), a subnucleus of the cholinergic basal ... -
Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior
BOKDE, ARUN; WHELAN, ROBERT (2017)Background Individual differences in impulsivity and early adversity are known to be strong predictors of adolescent antisocial behavior. However, the neurobiological bases of impulsivity and their relation to antisocial ... -
Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat
BOKDE, ARUN; WHELAN, ROBERT (2015)Cannabis use in adolescence may be characterized by differences in the neural basis of affective processing. In this study, we used an fMRI affective face processing task to compare a large group (n = 70) of 14-year olds ... -
Current Practice in the Referral of Individuals with Suspected Dementia for Neuroimaging by General Practitioners in Ireland and Wales
CIBLIS, AURELIA; BOKDE, ARUN (2016)Objectives While early diagnosis of dementia is important, the question arises whether general practitioners (GPs) should engage in direct referrals. The current study investigated current referral practices for ... -
Diagnostic power of default mode network resting state fMRI in the detection of Alzheimer's disease.
BOKDE, ARUN; HAMPEL, HARALD (2012)Functional magnetic resonance imaging (fMRI) of default mode network (DMN) brain activity during resting is recently gaining attention as a potential noninvasive biomarker to diagnose incipient Alzheimer's disease. The aim ... -
Dimensions of manic symptoms in youth: psychosocial impairment and cognitive performance in the IMAGEN sample.
BOKDE, ARUN (2014)It has been reported that mania may be associated with superior cognitive performance. In this study, we test the hypothesis that manic symptoms in youth separate along two correlated dimensions and that a symptom constellation ... -
Genomic architecture of human neuroanatomical diversity
BOKDE, ARUN (2014) -
Global genetic variations predict brain response to faces
BOKDE, ARUN (2014)Face expressions are a rich source of social signals. Here we estimated the proportion of phenotypic variance in the brain response to facial expressions explained by common genetic variance captured by ~500,000 single ... -
Healthy aging is associated with increased neural processing of positive valence but attenuated processing of emotional arousal: an fMRI study
KEHOE, ELIZABETH; BALSTERS, JOSHUA; BOKDE, ARUN (2013)Arousal and valence play key roles in emotional perception, with normal aging leading to changes in the neural substrates supporting valence processing. The objective of this study was to investigate normal age-related ... -
Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age?
WHELAN, ROBERT; BOKDE, ARUN; Bartholdy, Savani; Allen, Karina; Hodsoll, John; O'Daly, Owen G.; Campbell, Iain C.; Banaschewski, Tobias; Bromberg, Uli; Büchel, Christian; Burke Quinlan, Erin; Conrod, Patricia J.; Desrivieres, Sylvane; Flor, Herta; Frouin, Vincent; Gallinat, Jürgen; Garavan, Hugh; Heinz, Andreas; Ittermann, Bernd; Martinot, Jean-Luc; Artiges, Eric; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Paus, Tomáš; Poustka, Luise; Smolka, Michael N.; Mennigen, Eva; Walter, Henrik; Schumann, Gunter; Schmidt, Ulrike (2017)This study investigated the prevalence of disordered eating cognitions and behaviours across mid-adolescence in a large European sample, and explored the extent to which prevalence ratings were affected by informant ... -
The influence of study-level inference models and study set size on coordinate-based fMRI meta-analyses
BOKDE, ARUN (Frontiers Media, 2018)Given the increasing amount of neuroimaging studies, there is a growing need to summarize published results. Coordinate-based meta-analyses use the locations of statistically significant local maxima with possibly the ... -
Mouse and human genetic analyses associate kalirin with ventral striatal activation during impulsivity and with alcohol misuse
BOKDE, ARUN (2016)Impulsivity is associated with a spectrum of psychiatric disorders including drug addiction. To investigate genetic associations with impulsivity and initiation of drug taking, we took a two-step approach. First, we ... -
Neural circuitry underlying sustained attention in healthy adolescents and in ADHD symptomatology
BOKDE, ARUN; KELLY, CLARE; RUDDY, KATHY; WHELAN, ROBERT; O'Halloran, Laura; Cao, Zhipeng; Jollans, Lee; Albaugh, Matthew D.; Aleni, Andrea; Potter, Alexandra S.; Vahey, Nigel; Banaschewski, Tobias; Hohmann, Sarah; Bromberg, Uli; Büchel, Christian; Burke Quinlan, Erin; Desrivieres, Sylvane; Flor, Herta; Frouin, Vincent; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Paus, Tomáš; Smolka, Michael N.; Walter, Henrik; Schumann, Gunter; Garavan, Hugh (2017)Moment-to-moment reaction time variability on tasks of attention, often quantified by intra-individual response variability (IRV), provides a good indication of the degree to which an individual is vulnerable to lapses in ... -
Neuropsychosocial profiles of current and future adolescent alcohol misusers.
BOKDE, ARUN; WHELAN, ROBERT (2014)A comprehensive account of the causes of alcohol misuse must accommodate individual differences in biology, psychology and environment, and must disentangle cause and effect. Animal models can demonstrate the effects of ...