Browsing Radiation Therapy by Title
Now showing items 8-18 of 18
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Hypoxic Tumor Kinase Signaling Mediated by STAT5A in Development of Castration-Resistant Prostate Cancer.
(2013)In this study, we hypothesized that androgen-deprivation therapy (ADT) in prostate cancer, although initially efficient, induces changes in the tumor kinome, which subsequently promote development of castration-resistant ... -
In vitro modelling of androgen-mediated gene-directed enzyme prodrug therapy for the treatment of prostate cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2012)Gene-directed enzyme prodrug therapy has the potential to improve prostate cancer therapy outcome and could be used on its own or as an adjuvant to the current treatments. This research involved the characterisation of a ... -
Introduction to the ESTRO European Qualifications Framework (EQF) 7 and 8: Benchmarking Radiation Therapist (RTT) advanced education
(2018)Innovations in radiotherapy practice continue to develop and expand. With this comes a requirement for suitably educated Radiation TherapisTs (RTTs) to expand their scope of practice and work at advanced levels within ... -
Magnetic Resonance Imaging Radiomics - Towards the Personalisation of Radiation Therapy for Prostate Cancer.
(Trinity College Dublin. School of Medicine. Discipline of Radiation Therapy, 2020)The primary function of a predictive biomarker is to accurately determine the outcome of a specified treatment. Radiomics is a developing field that involves advanced image analysis and high throughput extraction of ... -
Multiplex profiling identifies clinically relevant signalling proteins in an isogenic prostate cancer model of radioresistance
(2019)The exact biological mechanism governing the radioresistant phenotype of prostate tumours at a high risk of recurrence despite the delivery of advanced radiotherapy protocols remains unclear. This study analysed the protein ... -
A promising set of candidate biomarkers of radioresistant prostate cancer
(Trinity College Dublin.School of Medicine.RADIATION THERAPY, 2016)Radiotherapy (RT) has a prominent role when used as a single modality or in combination with androgen deprivation therapy in the management of prostate cancer (CaP) patients. However, even with currently available high-dose ... -
Radiation oncology safety information system (ROSIS) : a reporting and learning system for radiation oncology
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2011)Background and Purpose: Incident reporting is a recognised tool for learning from incidents. The Radiation Oncology Safety Information System (ROSIS) was established in 2001, to collate and share information on incidents ... -
Radiation Therapists role in support patients in Radiation Oncology Departments
(2009-03-11)Despite advances in medical technology, cancer is still one of the leading causes of death globally, leaving many patients to deal with the emotional and psychological aspects associated with cancer and its treatment ... -
A review of the Best Practice in Radiation Oncology project from 2008 to 2018
(2018)The European Society of Radiotherapy and Oncology (ESTRO)/International Atomic Energy Agency (IAEA) Best Practice in Radiation Oncology-a project to train RTT trainers has reached its ten year anniversary and will commence ...