Optimisation of the synthesis and modification of CdTe quantum dots for enhanced live cell imaging
Citation:
S.J. Byrne, S.A. Corr, T.Y. Rakovich, Y.K. Gun'ko, Y.P. Rakovich, J.F. Donegan, S. Mitchell, Y. Volkov, `Optimisation of the synthesis and modification of CdTe quantum dots for enhanced live cell imaging? in Journal of Materials Chemistry, 16, 2006, pp 2896 - 2902Download Item:
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Abstract:
We report the preparation and luminescence enhancement of thioglycolic acid (TGA) stabilised
CdTe quantum dots (QDs) for use as live cell imaging tools in THP-1 macrophage cells. Short
irradiating times utilising a high powered Hg lamp resulted in increases in luminescence
efficiencies of up to y40% and permit significantly enhanced live imaging of the THP-1 cellular
components. It was found that the TGA-stabilised QDs traverse the cell membrane, illuminating
the cytoplasm and decorating the nuclear membrane. These studies highlight the potential use of
photoetched CdTe QDs as probes for specific in vitro labelling.
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Enterprise Ireland
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PUBLISHED
Author: RAKOVICH, YURY
Publisher:
Royal Society of ChemistryType of material:
Journal ArticleCollections:
Series/Report no:
Journal of Materials Chemistry16
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PhysicsISSN:
0959-9428Licences: