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dc.contributor.authorWOLFE, KENNETH
dc.date2006en
dc.date.accessioned2008-10-06T12:58:49Z
dc.date.available2008-10-06T12:58:49Z
dc.date.issued2006
dc.date.submitted2006en
dc.identifier.citationByrne, K. P. & Wolfe, K. H. `Visualizing syntenic relationships among the hemiascomycetes with the Yeast Gene Order Browser? in Nucleic Acids Research, 34, 2006, pp D452-455en
dc.identifier.issn0305-1048
dc.identifier.otherYen
dc.identifier.urihttp://hdl.handle.net/2262/22639
dc.descriptionPUBLISHEDen
dc.description.abstractThe Yeast Gene Order Browser (YGOB) is an online tool designed to facilitate the comparative genomic visualization and appraisal of synteny within and between the genomes of seven hemiascomycete yeast species. Three of these genomes are polyploid, and hence contain intra-genomic syntenic regions, the correct assembly of which is a particular success of YGOB. Designed to accurately assemble, display and score gene order relationships, YGOB is both an interactive tool for browsing genomic data, and a software engine now being used for evolutionary analyses on a whole-genome scale. Underlying the online interface is the YGOB database, which consists of homology assignments across the species, extensively curated based on sequence similarity and novelly, an appraisal of genomic context (synteny) in multiple genomes. Currently the YGOB database incorporates genome data from Saccharomyces cerevisiae, Candida glabrata, Saccharomyces castellii, Ashbya gossypii, Kluyveromyces lactis, Kluyveromyces waltii and Saccharomyces kluyveri, but the system is scaleable to accommodate additional genomes. This paper discusses the usage and utility of version 1.0 of YGOB, which is publicly available at http://wolfe.gen.tcd.ie/ygob.en
dc.format.extent2492267 bytes
dc.format.extentD452-455en
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherOxford University Pressen
dc.relation.ispartofseriesNucleic Acids Researchen
dc.relation.ispartofseries34en
dc.rightsYen
dc.subjectHuman genetics
dc.titleVisualizing syntenic relationships among the hemiascomycetes with the Yeast Gene Order Browseren
dc.typeJournal Articleen
dc.contributor.sponsorScience Foundation Ireland
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/khwolfe
dc.identifier.rssinternalid35976
dc.identifier.rssurihttp://dx.doi.org/10.1093/nar/gkj041


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