Recent Submissions

  • The use of the Caco-2 cell culture model to investigate lipid vehicle effects on lipid metabolism and drug permeation 

    Seeballuck, Fergal (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2004)
    The aim of this thesis was to assess the usefulness of the Caco-2 model for screening lipid vehicle excipient effects on intestinal lipoprotein production and secretion, with emphasis on chylomicron secretion. In addition, ...
  • Use of halloysite for agrochemical applications 

    Salter, Anne Elizabeth (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2004)
    The focus of this thesis was to develop two products for use in agrochemical applications, using the naturally occurring microtubular mineral, halloysite. Firstly, it was necessary to obtain a highly tubular grade of the ...
  • Potential applications of halloysite for improved topical drug delivery 

    Ryan, Catherine (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2007)
    The aim of this thesis was to evaluate the potential application of halloysite, an aluminosilicate clay material, for use in topical and transdermal drug delivery. Halloysite is a tubular material, the hollow lumen has ...
  • Transdermal delivery of somatostatin analogues 

    Loughman, Thomas Ciarán (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2002)
    The aim of this work was to develop transdermal delivery systems for the administration of two peptidic somatostatin analogues, BIM-23014 and its higher potency analogue BIM-23190. Due to its ability to suppress growth ...
  • Novel pharmaceutical excipients 

    Levis, Shane Reed (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2000)
    The research work performed in compiling this thesis can be divided into two broad areas, namely (a) the development, characterisation and examination of potential pharmaceutical applications of new de-aggregated grades ...

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