Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Author "MCCABE, THOMAS"
Now showing items 1-4 of 4
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Synthesis and antiproliferative action of a novel series of maprotiline analogues
(2014)The synthesis of a diverse library of compounds structurally related to maprotiline, a norepinephrine reuptake transporter (NET) selective antidepressant which has recently been identified as a novel in vitro antiproliferative ... -
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
(2011)A series of azetidin-2-ones substituted at positions 2, 3 and 4 of the azetidinone ring scaffold were synthesised and evaluated for antiproliferative, cytotoxic and tubulin binding activity. In these compounds, the cis ...
