Browsing Genetics (Scholarly Publications) by Title
Now showing items 120-139 of 356
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Further notes on the genealogy and social history of the Carlow family of John Tyndall (1820-1893)
(2013)Using local information and early correspondence we trace aspects of the history of the Carlow family of John Tyndall, concentrating particularly on his sister Emma and several hitherto unknown incidents in her life and ... -
A GATA/homeodomain transcriptional code regulates axon guidance through the Unc-5 receptor
(2012)Transcription factor codes play an essential role in neuronal specification and axonal guidance in both vertebrate and invertebrate organisms. However, how transcription codes regulate axon pathfinding remains poorly ... -
Gene dosage in the dysbindin schizophrenia susceptibility network differentially affect synaptic function and plasticity
(2015)Neurodevelopmental disorders arise from single or multiple gene defects. However, the way multiple loci interact to modify phenotypic outcomes remains poorly understood. Here, we studied phenotypes associated with mutations ... -
Gene expression changes during retinal development and rod specification
(2015)Purpose: Retinitis pigmentosa (RP) typically results from individual mutations in any one of >70 genes that cause rod photoreceptor cells to degenerate prematurely, eventually resulting in blindness. Gene therapies ... -
Gene expression profiles during early differentiation of mouse embryonic stem cells
(2009)Background Understanding the mechanisms controlling stem cell differentiation is the key to future advances in tissue and organ regeneration. Embryonic stem (ES) cell differentiation can be triggered by embryoid body ... -
Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection.
(2011)African bovine trypanosomiasis caused by Trypanosoma sp., is a major constraint on cattle productivity in sub-Saharan Africa. Some African Bos taurus breeds are highly tolerant of infection, but the potentially more ... -
Genetic evidence of African slavery at the beginning of the Trans-Atlantic slave trade
(2014)An archaeological excavation in Valle da Gafaria (Lagos, Portugal), revealed two contiguous burial places outside the medieval city walls, dating from the 15th-17th centuries AD: one was interpreted as a Leprosarium cemetery ... -
The genetics of brain wiring: from molecule to mind.
(2007)What makes some people neurotic or schizophrenic or right-handed or fearless? Are these behavioural differences caused by literal differences in how individuals' brains are wired? If so, what causes those differences? This ... -
The genetics of neurodevelopmental disease
(Elsevier, 2011)The term neurodevelopmental disorder encompasses a wide range of diseases, including recognizably distinct syndromes known to be caused by very rare mutations in specific genes or chromosomal loci, and also much more common ... -
Genome survey sequencing of the wine spoilage yeast Dekkera (Brettanomyces) bruxellensis.
(American Society for Microbiology, 2007)The hemiascomycete yeast Dekkera bruxellensis, also known as Brettanomyces bruxellensis, is a major cause of wine spoilage worldwide. Wines infected with D. bruxellensis develop distinctive, unpleasant aromas due to volatile ... -
A Genome Wide Association Scan of Bovine Tuberculosis Susceptibility in Holstein-Friesian Dairy Cattle
(2012)BACKGROUND: Bovine tuberculosis is a significant veterinary and financial problem in many parts of the world. Although many factors influence infection and progression of the disease, there is a host genetic component and ... -
Genome-wide analysis of gene expression during early Arabidopsis flower development
(Public Library of Science, 2006)Detailed information about stage-specific changes in gene expression is crucial for the understanding of the gene regulatory networks underlying development. Here, we describe the global gene expression dynamics during ... -
Genome-wide association study for calving traits in Holstein-Friesian dairy cattle
(2014)The enteropathogen Campylobacter jejuni is a major worldwide health and economic burden, being one of the leading causes of bacterial gastroenteritis and commonly linked to postinfectious onset of autoimmune disease. ... -
A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23
(2016)Background Bovine tuberculosis (bTB) infection in cattle is a significant economic concern in many countries, with annual costs to the UK and Irish governments of approximately €190 million and €63 million, respectively, ... -
A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility
(2013)Mastitis is an inflammation-driven disease of the bovine mammary gland that occurs in response to physical damage or infection and is one of the most costly production-related diseases in the dairy industry worldwide. We ... -
Genome-wide associations for milk production and somatic cell score in Holstein-Friesian cattle in Ireland
(2012)Background: Contemporary dairy breeding goals have broadened to include, along with milk production traits, a number of non-production-related traits in an effort to improve the overall functionality of the dairy cow. ... -
Genome-wide data from two early Neolithic East Asian individuals dating to 7700 years ago
(2017)Ancient genomes have revolutionized our understanding of Holocene prehistory and, particularly, the Neolithic transition in western Eurasia. In contrast, East Asia has so far received little attention, despite ... -
Genome-wide deserts for copy number variation in vertebrates
(2013)Most copy number variations are neutral, but some are deleterious and associated with various human diseases. Copy number variations are distributed non-randomly in vertebrate genomes, and it was recently reported that ...